
Esomeprazole (40mg) + Domperidone (30mg)
Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Impraon-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30mg and Esomeprazole 40mg, indicated for the management of gastroesophageal reflux disease (GERD), dyspepsia, and other acid-related gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, promoting mucosal healing and reducing acid reflux. The synergistic action of these agents provides effective symptomatic relief and enhances mucosal protection in patients with erosive esophagitis and non-erosive reflux disease. Impraon-DSR is typically administered orally once daily, preferably before meals, to optimize therapeutic outcomes. Caution is advised in patients with known hypersensitivity to either component, and it should be used judiciously in individuals with hepatic impairment or prolactinoma. Common adverse effects may include headache, dry mouth, and abdominal discomfort. This combination therapy should be prescribed under medical supervision, with periodic evaluation to assess efficacy and monitor for potential side effects. Impraon-DSR Capsule offers a comprehensive approach to managing acid-related gastrointestinal conditions by combining prokinetic and acid suppression mechanisms.
How to use Impraon-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Impraon-DSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Impraon-DSR Capsule. Please consult your doctor.
High Risk
Impraon-DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Impraon-DSR Capsule is safe to use in patients with liver disease. No dose adjustment of Impraon-DSR Capsule is recommended.
Regular Checkup
Impraon-DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Impraon-DSR Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Impraon-DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Impraon-DSR Capsule

Domperidone (30mg) + Esomeprazole (40mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Impraon-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30mg and Esomeprazole 40mg, indicated for the management of gastroesophageal reflux disease (GERD), dyspepsia, and other acid-related gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, promoting mucosal healing and reducing acid reflux. The synergistic action of these agents provides effective symptomatic relief and enhances mucosal protection in patients with erosive esophagitis and non-erosive reflux disease. Impraon-DSR is typically administered orally once daily, preferably before meals, to optimize therapeutic outcomes. Caution is advised in patients with known hypersensitivity to either component, and it should be used judiciously in individuals with hepatic impairment or prolactinoma. Common adverse effects may include headache, dry mouth, and abdominal discomfort. This combination therapy should be prescribed under medical supervision, with periodic evaluation to assess efficacy and monitor for potential side effects. Impraon-DSR Capsule offers a comprehensive approach to managing acid-related gastrointestinal conditions by combining prokinetic and acid suppression mechanisms.
How to use Impraon-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Impraon-DSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Impraon-DSR Capsule. Please consult your doctor.
High Risk
Impraon-DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Impraon-DSR Capsule is safe to use in patients with liver disease. No dose adjustment of Impraon-DSR Capsule is recommended.
Regular Checkup
Impraon-DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consult Doctor
Impraon-DSR Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Impraon-DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Impraon-DSR Capsule















