Ikgdar 500mg Injection
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Vial of 50 ml • LiquidPrescription requiredSchedule H
Ikgdar 500mg Injection
Rituximab (500mg)
₹38045.00
Vial of 50 ml • Liquid
A valid prescription is required for this medicine.
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Active composition
Rituximab 500 mg
How It Works
Rituximab binds to CD20 on B-cells, inducing apoptosis and mediating antibody-dependent cellular cytotoxicity.
Medicine Strength
500 mg
Uses & Benefits
Medical applications
Rheumatoid ArthritisInfection
Ikgdar 500mg Injection contains Rituximab, a chimeric monoclonal antibody targeting the CD20 antigen found on the surface of B-lymphocytes. Rituximab is indicated for the treatment of various B-cell malignancies, including non-Hodgkin’s lymphoma, chronic lymphocytic leukemia, and certain autoimmune disorders such as rheumatoid arthritis. The mechanism of action involves selective binding to the CD20 antigen, leading to B-cell depletion through complement-dependent cytotoxicity, antibody-dependent cellular cytotoxicity, and induction of apoptosis.
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Ikgdar 500mg Injection is administered intravenously under strict medical supervision, with dosing regimens tailored to the specific indication and patient response. Prior to infusion, premedication with antihistamines and corticosteroids is recommended to reduce the risk of infusion-related reactions. Patients should be monitored closely for adverse effects, including infusion reactions, infections, and hematologic toxicities.
Rituximab therapy requires careful evaluation of patient history, including screening for hepatitis B virus and other infections. The use of Ikgdar 500mg Injection should be reserved for conditions where B-cell depletion is clinically justified, and treatment should be conducted by healthcare professionals experienced in monoclonal antibody therapies. Proper storage and handling are essential to maintain drug stability and efficacy.
Dosage & How to Use
Monoclonal antibody (mAb)
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Pregnancy
Ikgdar 500mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Driving
Ikgdar 500mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Ikgdar 500mg Injection may not be needed in these patients. Please consult your doctor.
Exercise Caution
Breastfeeding
It is not known whether Ikgdar 500mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Consult Doctor
Kidney
There is limited information available on the use of Ikgdar 500mg Injection in patients with liver disease. Please consult your doctor. Use of Ikgdar 500mg Injection is not recommended in patients with the active liver disease or those who had viral hepatitis as it can reactivate the infection.
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