Ifsamide-M Injection
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Box of 1 injection • OtherPrescription requiredSchedule H
Ifsamide-M Injection
Mesna (100mg/ml) + Ifosfamide (1gm)
₹461.37
Box of 1 injection • Other
A valid prescription is required for this medicine.
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Active composition
Ifosfamide 1 gm
+1 more active ingredient
How It Works
Ifosfamide forms DNA cross-links, preventing DNA replication and transcription in cancer cells, leading to apoptosis.
Mesna reacts with urotoxic metabolites, neutralizing their harmful effects on the bladder.
Medicine Strength
1 gm
All Active Ingredients
Ifosfamide1 gm
Mesna
Uses & Benefits
Medical applications
Ifsamide-M Injection is a sterile, injectable formulation combining Mesna (100 mg/ml) and Ifosfamide (1 g) designed for intravenous administration in oncological therapy. Ifosfamide, an alkylating agent, exerts cytotoxic effects by cross-linking DNA strands, thereby inhibiting DNA synthesis and inducing apoptosis in rapidly dividing malignant cells. Mesna serves as a uroprotective agent, effectively binding and detoxifying acrolein, a toxic metabolite of Ifosfamide, thus preventing hemorrhagic cystitis and other urothelial toxicities commonly associated with Ifosfamide therapy.
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The combination enhances therapeutic efficacy while minimizing adverse effects related to bladder toxicity. Ifsamide-M Injection is indicated for the treatment of various malignancies, including sarcomas, lymphomas, and testicular cancer, either as monotherapy or in combination with other chemotherapeutic agents. Dosage and administration should be individualized based on patient condition, tumor type, and treatment protocol, with careful monitoring of renal function, hematologic parameters, and hydration status.
Adverse reactions may include myelosuppression, neurotoxicity, nephrotoxicity, and gastrointestinal disturbances. Appropriate supportive care and monitoring are essential to optimize treatment outcomes. This combination injection should be administered under strict medical supervision in a hospital or specialized oncology setting.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Pregnancy
Ifsamide-M Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Medical Advice
Driving
Ifsamide-M Injection should be used with caution in patients with kidney disease. Dose adjustment of Ifsamide-M Injection may be needed. Please consult your doctor.
Exercise Caution
Breastfeeding
Ifsamide-M Injection may cause side effects which could affect your ability to drive.
Consult Doctor
Kidney
Ifsamide-M Injection should be used with caution in patients with liver disease. Dose adjustment of Ifsamide-M Injection may be needed. Please consult your doctor.
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