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  4. Ifosym 1g Injection
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Ifosym 1g Injection

Images are for reference. Actual packaging may vary.

Vial of 1 injection • InjectionPrescription requiredSchedule H

Ifosym 1g Injection

Mesna (100mg/ml) + Ifosfamide (1gm)

Symbion Lifescienceanti-cancer
₹536.12

Vial of 1 injection • Injection

A valid prescription is required for this medicine.

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Active composition

Mesna

+1 more active ingredient

How It Works

Mesna reacts with urotoxic metabolites, neutralizing their harmful effects on the bladder.

Ifosfamide forms DNA cross-links, preventing DNA replication and transcription in cancer cells, leading to apoptosis.

All Active Ingredients

Mesna
Ifosfamide1 gm

Uses & Benefits

Medical applications

Ifosym 1g Injection is a combination pharmaceutical preparation containing Ifosfamide 1g and Mesna 100mg/ml, indicated for use in oncological chemotherapy protocols. Ifosfamide, an alkylating agent of the oxazaphosphorine class, exerts cytotoxic effects by cross-linking DNA strands, thereby inhibiting DNA synthesis and inducing apoptosis in rapidly proliferating malignant cells.

Read full descriptionShow less⌄

Mesna, a uroprotective agent, is co-administered to mitigate the urothelial toxicity associated with Ifosfamide, particularly hemorrhagic cystitis, by binding to and detoxifying acrolein, a toxic metabolite of Ifosfamide excreted in the urine. Ifosym 1g Injection is primarily utilized in the treatment of various malignancies including sarcomas, lymphomas, and testicular cancer, often as part of combination chemotherapy regimens.

The injection is administered intravenously under strict medical supervision, with dosing individualized based on patient-specific factors such as body surface area, renal function, and treatment response. Close monitoring for potential adverse effects including myelosuppression, neurotoxicity, nephrotoxicity, and electrolyte imbalances is essential. Adequate hydration and Mesna dosing are critical to reduce urothelial toxicity.

Ifosym 1g Injection should be handled and administered by trained healthcare professionals experienced in chemotherapy management to optimize therapeutic outcomes and minimize risks.

Ifosym 1g Injection packaging
Medicine details

Ifosym 1g Injection

Composition

2 ingredients
  • Mesna100 mg/ml
  • Ifosfamide1 gm
Dosage & how to useRead the usage informationSafety & side effectsReview precautions

Dosage & How to Use

Dosage information not available. Please consult your doctor or pharmacist.

Safety Advice

Important precautions

Side effects

Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.

Safety Advice

Pregnancy

Ifosym 1g Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Medical Advice

Driving

Ifosym 1g Injection should be used with caution in patients with kidney disease. Dose adjustment of Ifosym 1g Injection may be needed. Please consult your doctor.

Exercise Caution

Breastfeeding

Ifosym 1g Injection may cause side effects which could affect your ability to drive.

Consult Doctor

Kidney

Ifosym 1g Injection should be used with caution in patients with liver disease. Dose adjustment of Ifosym 1g Injection may be needed. Please consult your doctor.

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