
Rabeprazole (20mg) + Domperidone (30mg)
Active composition
+1 more active ingredient
Rabeprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Hyreb-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30 mg and Rabeprazole 20 mg, indicated for the treatment of gastroesophageal reflux disease (GERD), dyspepsia, and related upper gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating. Rabeprazole, a proton pump inhibitor, suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, promoting mucosal healing and symptom relief. The synergistic action of these two agents addresses both the underlying acid hypersecretion and impaired gastric motility, offering comprehensive symptom control. Hyreb-DSR is typically administered orally once daily before meals, with dosage adjustments based on clinical response and tolerability. It is contraindicated in patients with known hypersensitivity to either component, and caution is advised in individuals with hepatic impairment or prolactin-secreting pituitary tumors. Common adverse effects may include headache, dry mouth, abdominal cramps, and diarrhea. Patients should consult healthcare professionals prior to use, especially if pregnant, breastfeeding, or on concurrent medications to avoid potential drug interactions. Hyreb-DSR Capsule provides an effective therapeutic option for managing acid-related gastrointestinal conditions with improved patient compliance.
How to use Hyreb-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hyreb-DSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Hyreb-DSR Capsule. Please consult your doctor.
High Risk
Hyreb-DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Hyreb-DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Hyreb-DSR Capsule should be used with caution in patients with liver disease. Dose adjustment of Hyreb-DSR Capsule may be needed. Please consult your doctor. Use of Hyreb-DSR Capsule is not recommended in patients with moderate and severe liver disease.
Regular Checkup
Hyreb-DSR Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Hyreb-DSR Capsule should be used with caution in patients with kidney disease. Dose adjustment of Hyreb-DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Hyreb-DSR Capsule

Domperidone (30mg) + Rabeprazole (20mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Rabeprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Hyreb-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30 mg and Rabeprazole 20 mg, indicated for the treatment of gastroesophageal reflux disease (GERD), dyspepsia, and related upper gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating. Rabeprazole, a proton pump inhibitor, suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, promoting mucosal healing and symptom relief. The synergistic action of these two agents addresses both the underlying acid hypersecretion and impaired gastric motility, offering comprehensive symptom control. Hyreb-DSR is typically administered orally once daily before meals, with dosage adjustments based on clinical response and tolerability. It is contraindicated in patients with known hypersensitivity to either component, and caution is advised in individuals with hepatic impairment or prolactin-secreting pituitary tumors. Common adverse effects may include headache, dry mouth, abdominal cramps, and diarrhea. Patients should consult healthcare professionals prior to use, especially if pregnant, breastfeeding, or on concurrent medications to avoid potential drug interactions. Hyreb-DSR Capsule provides an effective therapeutic option for managing acid-related gastrointestinal conditions with improved patient compliance.
How to use Hyreb-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hyreb-DSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Hyreb-DSR Capsule. Please consult your doctor.
High Risk
Hyreb-DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Hyreb-DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Hyreb-DSR Capsule should be used with caution in patients with liver disease. Dose adjustment of Hyreb-DSR Capsule may be needed. Please consult your doctor. Use of Hyreb-DSR Capsule is not recommended in patients with moderate and severe liver disease.
Regular Checkup
Hyreb-DSR Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Hyreb-DSR Capsule should be used with caution in patients with kidney disease. Dose adjustment of Hyreb-DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Hyreb-DSR Capsule















