
Hydroxyurea (500mg)
Active composition
Hydroxyurea inhibits ribonucleotide reductase, leading to decreased DNA synthesis and increased fetal hemoglobin production in sickle cell disease.
Medical applications
Hydromac 500 Capsule contains Hydroxyurea 500 mg, an antineoplastic agent primarily used in the management of various hematologic disorders. Hydroxyurea acts by inhibiting ribonucleotide reductase, thereby interfering with DNA synthesis and exerting cytotoxic effects on rapidly dividing cells. It is commonly prescribed for conditions such as chronic myeloid leukemia, sickle cell anemia, and certain myeloproliferative disorders including polycythemia vera and essential thrombocythemia. In sickle cell anemia, Hydroxyurea increases fetal hemoglobin production, reducing the frequency of painful crises and the need for blood transfusions. The drug is administered orally, with dosage individualized based on the patient’s clinical response and hematologic parameters. Common adverse effects include myelosuppression, gastrointestinal disturbances, and dermatologic reactions; therefore, regular monitoring of blood counts and renal and hepatic function is essential during therapy. Contraindications include pregnancy, breastfeeding, and severe bone marrow suppression. Caution is advised in patients with renal or hepatic impairment. Hydromac 500 Capsule should be used under strict medical supervision to optimize therapeutic outcomes and minimize potential toxicity. Patients are advised to adhere to prescribed dosing schedules and report any adverse symptoms promptly to their healthcare provider.
How to use Hydromac Capsule Take this medicine in the dose and duration as advised by your doctor. Hydromac 500 Capsule may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is not known whether it is safe to consume alcohol with Hydromac 500 Capsule. Please consult your doctor.
High Risk
Hydromac 500 Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Medical Advice
Hydromac 500 Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Hydromac 500 Capsule should be used with caution in patients with liver disease. Dose adjustment of Hydromac 500 Capsule may be needed. Please consult your doctor.
Regular Checkup
Hydromac 500 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Hydromac 500 Capsule should be used with caution in patients with kidney disease. Dose adjustment of Hydromac 500 Capsule may be needed. Please consult your doctor. Regular monitoring of kidney function and some blood tests may be advised while taking this medicine.
Regular Checkup
0 reviews for Hydromac 500 Capsule

Hydroxyurea (500mg)
Cheaper alternative availability
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Active composition
Hydroxyurea inhibits ribonucleotide reductase, leading to decreased DNA synthesis and increased fetal hemoglobin production in sickle cell disease.
Medical applications
Hydromac 500 Capsule contains Hydroxyurea 500 mg, an antineoplastic agent primarily used in the management of various hematologic disorders. Hydroxyurea acts by inhibiting ribonucleotide reductase, thereby interfering with DNA synthesis and exerting cytotoxic effects on rapidly dividing cells. It is commonly prescribed for conditions such as chronic myeloid leukemia, sickle cell anemia, and certain myeloproliferative disorders including polycythemia vera and essential thrombocythemia. In sickle cell anemia, Hydroxyurea increases fetal hemoglobin production, reducing the frequency of painful crises and the need for blood transfusions. The drug is administered orally, with dosage individualized based on the patient’s clinical response and hematologic parameters. Common adverse effects include myelosuppression, gastrointestinal disturbances, and dermatologic reactions; therefore, regular monitoring of blood counts and renal and hepatic function is essential during therapy. Contraindications include pregnancy, breastfeeding, and severe bone marrow suppression. Caution is advised in patients with renal or hepatic impairment. Hydromac 500 Capsule should be used under strict medical supervision to optimize therapeutic outcomes and minimize potential toxicity. Patients are advised to adhere to prescribed dosing schedules and report any adverse symptoms promptly to their healthcare provider.
How to use Hydromac Capsule Take this medicine in the dose and duration as advised by your doctor. Hydromac 500 Capsule may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is not known whether it is safe to consume alcohol with Hydromac 500 Capsule. Please consult your doctor.
High Risk
Hydromac 500 Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Medical Advice
Hydromac 500 Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Hydromac 500 Capsule should be used with caution in patients with liver disease. Dose adjustment of Hydromac 500 Capsule may be needed. Please consult your doctor.
Regular Checkup
Hydromac 500 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Hydromac 500 Capsule should be used with caution in patients with kidney disease. Dose adjustment of Hydromac 500 Capsule may be needed. Please consult your doctor. Regular monitoring of kidney function and some blood tests may be advised while taking this medicine.
Regular Checkup
0 reviews for Hydromac 500 Capsule















