
Rabeprazole (20mg) + Itopride (150mg)
Active composition
+1 more active ingredient
Rabeprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
Itopride increases acetylcholine levels, enhancing gastrointestinal motility and facilitating food movement through the digestive tract.
Medical applications
HSP-IT Capsule SR is a combination medication containing Rabeprazole 20 mg and Itopride 150 mg, formulated for sustained release to provide effective management of gastrointestinal disorders. Rabeprazole, a proton pump inhibitor, acts by selectively inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, thereby suppressing gastric acid secretion and promoting ulcer healing. Itopride, a prokinetic agent, enhances gastrointestinal motility by antagonizing dopamine D2 receptors and inhibiting acetylcholinesterase activity, facilitating gastric emptying and alleviating symptoms such as bloating, nausea, and early satiety. The combined action of Rabeprazole and Itopride in HSP-IT Capsule SR is particularly beneficial in treating conditions like gastroesophageal reflux disease (GERD), functional dyspepsia, and peptic ulcer disease where both acid suppression and improved motility are required. The sustained-release formulation ensures prolonged therapeutic effect, improving patient compliance by reducing dosing frequency. HSP-IT Capsule SR should be used under medical supervision, considering contraindications such as hypersensitivity to its components, and with caution in patients with hepatic or renal impairment. Common adverse effects may include headache, diarrhea, or abdominal discomfort. This combination therapy offers a comprehensive approach to managing upper gastrointestinal symptoms by targeting multiple pathophysiological mechanisms.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
HSP-IT Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Information regarding the use of HSP-IT Capsule SR during breastfeeding is not available. Please consult your doctor.
Medical Advice
There is limited information available on the use of HSP-IT Capsule SR in patients with kidney disease. Please consult your doctor.
Exercise Caution
HSP-IT Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
HSP-IT Capsule SR should be used with caution in patients with severe liver disease. Dose adjustment of HSP-IT Capsule SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for HSP-IT Capsule SR

Rabeprazole (20mg) + Itopride (150mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Rabeprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
Itopride increases acetylcholine levels, enhancing gastrointestinal motility and facilitating food movement through the digestive tract.
Medical applications
HSP-IT Capsule SR is a combination medication containing Rabeprazole 20 mg and Itopride 150 mg, formulated for sustained release to provide effective management of gastrointestinal disorders. Rabeprazole, a proton pump inhibitor, acts by selectively inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, thereby suppressing gastric acid secretion and promoting ulcer healing. Itopride, a prokinetic agent, enhances gastrointestinal motility by antagonizing dopamine D2 receptors and inhibiting acetylcholinesterase activity, facilitating gastric emptying and alleviating symptoms such as bloating, nausea, and early satiety. The combined action of Rabeprazole and Itopride in HSP-IT Capsule SR is particularly beneficial in treating conditions like gastroesophageal reflux disease (GERD), functional dyspepsia, and peptic ulcer disease where both acid suppression and improved motility are required. The sustained-release formulation ensures prolonged therapeutic effect, improving patient compliance by reducing dosing frequency. HSP-IT Capsule SR should be used under medical supervision, considering contraindications such as hypersensitivity to its components, and with caution in patients with hepatic or renal impairment. Common adverse effects may include headache, diarrhea, or abdominal discomfort. This combination therapy offers a comprehensive approach to managing upper gastrointestinal symptoms by targeting multiple pathophysiological mechanisms.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
HSP-IT Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Information regarding the use of HSP-IT Capsule SR during breastfeeding is not available. Please consult your doctor.
Medical Advice
There is limited information available on the use of HSP-IT Capsule SR in patients with kidney disease. Please consult your doctor.
Exercise Caution
HSP-IT Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
HSP-IT Capsule SR should be used with caution in patients with severe liver disease. Dose adjustment of HSP-IT Capsule SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for HSP-IT Capsule SR















