
Domperidone (30mg) + Rabeprazole (20mg)
Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Rabeprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
Medical applications
Holyrab-D Capsule SR is a combination pharmaceutical formulation containing Domperidone 30 mg and Rabeprazole 20 mg, designed for the management of gastrointestinal disorders characterized by acid-related symptoms and motility disturbances. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric emptying and enhances gastrointestinal motility, thereby alleviating symptoms such as nausea, vomiting, bloating, and early satiety. Rabeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, providing effective relief from acid-related conditions including gastroesophageal reflux disease (GERD), peptic ulcers, and erosive esophagitis. The sustained-release (SR) formulation ensures prolonged therapeutic plasma concentrations, improving patient compliance and symptom control. Holyrab-D Capsule SR is indicated for patients requiring combined acid suppression and prokinetic therapy, particularly in cases where delayed gastric emptying exacerbates acid reflux symptoms. It is recommended to be taken orally as prescribed by a healthcare professional. Caution is advised in patients with known hypersensitivity to either component, cardiac arrhythmias, or severe hepatic impairment. Regular monitoring and adherence to prescribed dosage are essential to optimize therapeutic outcomes and minimize adverse effects.
How to use Holyrab-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Holyrab-D Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Holyrab-D Capsule SR. Please consult your doctor.
High Risk
Holyrab-D Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Holyrab-D Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Holyrab-D Capsule SR should be used with caution in patients with liver disease. Dose adjustment of Holyrab-D Capsule SR may be needed. Please consult your doctor. Use of Holyrab-D Capsule SR is not recommended in patients with moderate and severe liver disease.
Regular Checkup
Holyrab-D Capsule SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Holyrab-D Capsule SR should be used with caution in patients with kidney disease. Dose adjustment of Holyrab-D Capsule SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Holyrab-D Capsule SR

Domperidone (30mg) + Rabeprazole (20mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Rabeprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
Medical applications
Holyrab-D Capsule SR is a combination pharmaceutical formulation containing Domperidone 30 mg and Rabeprazole 20 mg, designed for the management of gastrointestinal disorders characterized by acid-related symptoms and motility disturbances. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric emptying and enhances gastrointestinal motility, thereby alleviating symptoms such as nausea, vomiting, bloating, and early satiety. Rabeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, providing effective relief from acid-related conditions including gastroesophageal reflux disease (GERD), peptic ulcers, and erosive esophagitis. The sustained-release (SR) formulation ensures prolonged therapeutic plasma concentrations, improving patient compliance and symptom control. Holyrab-D Capsule SR is indicated for patients requiring combined acid suppression and prokinetic therapy, particularly in cases where delayed gastric emptying exacerbates acid reflux symptoms. It is recommended to be taken orally as prescribed by a healthcare professional. Caution is advised in patients with known hypersensitivity to either component, cardiac arrhythmias, or severe hepatic impairment. Regular monitoring and adherence to prescribed dosage are essential to optimize therapeutic outcomes and minimize adverse effects.
How to use Holyrab-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Holyrab-D Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Holyrab-D Capsule SR. Please consult your doctor.
High Risk
Holyrab-D Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Holyrab-D Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Holyrab-D Capsule SR should be used with caution in patients with liver disease. Dose adjustment of Holyrab-D Capsule SR may be needed. Please consult your doctor. Use of Holyrab-D Capsule SR is not recommended in patients with moderate and severe liver disease.
Regular Checkup
Holyrab-D Capsule SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Holyrab-D Capsule SR should be used with caution in patients with kidney disease. Dose adjustment of Holyrab-D Capsule SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Holyrab-D Capsule SR















