
Domperidone (30mg) + Rabeprazole (20mg)
Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Rabeprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
Medical applications
Hirabezol D 30mg/20mg Capsule is a combination pharmaceutical formulation containing Domperidone 30mg and Rabeprazole 20mg, indicated for the management of gastroesophageal reflux disease (GERD), dyspepsia, and related acid-peptic disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating. Rabeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, promoting mucosal healing and symptom relief in acid-related conditions. The synergistic action of these agents provides both symptomatic relief and addresses the underlying pathophysiology of acid reflux and delayed gastric emptying. Hirabezol D is typically administered orally once daily, preferably before meals, with dosage adjustments based on clinical response and tolerability. Common adverse effects may include headache, dry mouth, abdominal discomfort, and, rarely, extrapyramidal symptoms due to Domperidone. Caution is advised in patients with cardiac arrhythmias, hepatic impairment, or those on concomitant medications that prolong the QT interval. Hirabezol D should be used under medical supervision, with monitoring for efficacy and potential side effects to ensure optimal therapeutic outcomes.
How to use Hirabezol D Capsule Take this medicine in the dose and duration as advised by your doctor. Hirabezol D 30mg/20mg Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Hirabezol D 30mg/20mg Capsule. Please consult your doctor.
High Risk
Hirabezol D 30mg/20mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Hirabezol D 30mg/20mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Hirabezol D 30mg/20mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Hirabezol D 30mg/20mg Capsule may be needed. Please consult your doctor. Use of Hirabezol D 30mg/20mg Capsule is not recommended in patients with moderate and severe liver disease.
Regular Checkup
Hirabezol D 30mg/20mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Hirabezol D 30mg/20mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Hirabezol D 30mg/20mg Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Hirabezol D 30mg/20mg Capsule

Domperidone (30mg) + Rabeprazole (20mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Rabeprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
Medical applications
Hirabezol D 30mg/20mg Capsule is a combination pharmaceutical formulation containing Domperidone 30mg and Rabeprazole 20mg, indicated for the management of gastroesophageal reflux disease (GERD), dyspepsia, and related acid-peptic disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating. Rabeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, promoting mucosal healing and symptom relief in acid-related conditions. The synergistic action of these agents provides both symptomatic relief and addresses the underlying pathophysiology of acid reflux and delayed gastric emptying. Hirabezol D is typically administered orally once daily, preferably before meals, with dosage adjustments based on clinical response and tolerability. Common adverse effects may include headache, dry mouth, abdominal discomfort, and, rarely, extrapyramidal symptoms due to Domperidone. Caution is advised in patients with cardiac arrhythmias, hepatic impairment, or those on concomitant medications that prolong the QT interval. Hirabezol D should be used under medical supervision, with monitoring for efficacy and potential side effects to ensure optimal therapeutic outcomes.
How to use Hirabezol D Capsule Take this medicine in the dose and duration as advised by your doctor. Hirabezol D 30mg/20mg Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Hirabezol D 30mg/20mg Capsule. Please consult your doctor.
High Risk
Hirabezol D 30mg/20mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Hirabezol D 30mg/20mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Hirabezol D 30mg/20mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Hirabezol D 30mg/20mg Capsule may be needed. Please consult your doctor. Use of Hirabezol D 30mg/20mg Capsule is not recommended in patients with moderate and severe liver disease.
Regular Checkup
Hirabezol D 30mg/20mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Hirabezol D 30mg/20mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Hirabezol D 30mg/20mg Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Hirabezol D 30mg/20mg Capsule















