
Esomeprazole (40mg) + Domperidone (30mg)
Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Harzole-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30mg and Esomeprazole 40mg, designed for the effective management of gastroesophageal reflux disease (GERD), acid reflux, and related upper gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, bloating, and gastric discomfort. Esomeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in gastric parietal cells, providing sustained acid suppression and promoting mucosal healing. The synergistic action of these two agents in Harzole-DSR Capsule offers comprehensive relief from acid-related symptoms and enhances patient compliance by combining prokinetic and acid-suppressive therapies in a single dosage form. This combination is particularly beneficial for patients with erosive esophagitis, Zollinger-Ellison syndrome, or those requiring prolonged acid suppression alongside improved gastric motility. Harzole-DSR should be administered as prescribed by a healthcare professional, with consideration of contraindications such as hypersensitivity to either component, and caution in patients with cardiac arrhythmias or hepatic impairment. Adverse effects may include headache, dry mouth, abdominal cramps, or diarrhea. Regular monitoring and adherence to prescribed dosage ensure optimal therapeutic outcomes.
How to use Harzole-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Harzole-DSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Harzole-DSR Capsule. Please consult your doctor.
High Risk
Harzole-DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Harzole-DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Harzole-DSR Capsule is safe to use in patients with liver disease. No dose adjustment of Harzole-DSR Capsule is recommended.
Regular Checkup
Harzole-DSR Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Harzole-DSR Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Harzole-DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Harzole-DSR Capsule

Domperidone (30mg) + Esomeprazole (40mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Harzole-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30mg and Esomeprazole 40mg, designed for the effective management of gastroesophageal reflux disease (GERD), acid reflux, and related upper gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, bloating, and gastric discomfort. Esomeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in gastric parietal cells, providing sustained acid suppression and promoting mucosal healing. The synergistic action of these two agents in Harzole-DSR Capsule offers comprehensive relief from acid-related symptoms and enhances patient compliance by combining prokinetic and acid-suppressive therapies in a single dosage form. This combination is particularly beneficial for patients with erosive esophagitis, Zollinger-Ellison syndrome, or those requiring prolonged acid suppression alongside improved gastric motility. Harzole-DSR should be administered as prescribed by a healthcare professional, with consideration of contraindications such as hypersensitivity to either component, and caution in patients with cardiac arrhythmias or hepatic impairment. Adverse effects may include headache, dry mouth, abdominal cramps, or diarrhea. Regular monitoring and adherence to prescribed dosage ensure optimal therapeutic outcomes.
How to use Harzole-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Harzole-DSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Harzole-DSR Capsule. Please consult your doctor.
High Risk
Harzole-DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Harzole-DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Harzole-DSR Capsule is safe to use in patients with liver disease. No dose adjustment of Harzole-DSR Capsule is recommended.
Regular Checkup
Harzole-DSR Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Harzole-DSR Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Harzole-DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Harzole-DSR Capsule















