Hanclo Cream
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Clobetasol (0.05% w/w) + Miconazole (2% w/w) + Neomycin (0.2% w/w)
Tube of 10 gm • Gel
A valid prescription is required for this medicine.
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Active composition
+2 more active ingredients
Neomycin binds to the 30S ribosomal subunit of bacteria, inhibiting protein synthesis and leading to bacterial cell death.
Clobetasol binds to glucocorticoid receptors, inhibiting the transcription of pro-inflammatory genes and reducing inflammation.
Miconazole inhibits the synthesis of ergosterol, compromising fungal cell membrane integrity and leading to cell death.
Medical applications
Hanclo Cream is a topical formulation combining Clobetasol propionate (0.05% w/w), Miconazole nitrate (2% w/w), and Neomycin sulfate (0.2% w/w), designed for the effective management of inflammatory dermatoses complicated by fungal and bacterial infections. Clobetasol, a potent corticosteroid, exerts strong anti-inflammatory, antipruritic, and vasoconstrictive effects, thereby reducing redness, swelling, and itching associated with various skin conditions.
Miconazole, an imidazole antifungal agent, inhibits ergosterol synthesis in fungal cell membranes, providing broad-spectrum activity against dermatophytes, yeasts, and other fungi. Neomycin, an aminoglycoside antibiotic, targets susceptible gram-positive and gram-negative bacteria by inhibiting protein synthesis, thereby preventing or treating secondary bacterial infections. The synergistic combination in Hanclo Cream is particularly beneficial in conditions such as eczema, psoriasis, and dermatitis when complicated by mixed infections.
It should be applied topically as directed by a healthcare professional, avoiding prolonged use to minimize potential adverse effects such as skin atrophy, irritation, or systemic absorption. Caution is advised in patients with known hypersensitivity to any component. Hanclo Cream is intended for external use only and should not be applied to open wounds or mucous membranes. Proper adherence to prescribed usage ensures optimal therapeutic outcomes.
How to use Hanclo Cream This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
No interaction found/established
High Risk
Hanclo Cream may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
No interaction found/established
Exercise Caution
No interaction found/established
Regular Checkup
Hanclo Cream is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
No interaction found/established
Regular Checkup
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