Grazirate OD 250 Tablet ER
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1 units • OtherPrescription requiredSchedule H
Grazirate OD 250 Tablet ER
Divalproex (250mg)
₹89.00
1 units • Other
A valid prescription is required for this medicine.
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Active composition
Divalproex 250 mg
How It Works
Divalproex increases GABA levels in the brain, enhancing inhibitory neurotransmission and stabilizing neuronal activity.
Medicine Strength
250 mg
Uses & Benefits
Medical applications
HeadacheMigraine
Grazirate OD 250 Tablet ER contains divalproex sodium 250 mg, an extended-release formulation designed to provide sustained therapeutic effects. Divalproex is a valproate compound that acts as an anticonvulsant and mood stabilizer, primarily used in the management of epilepsy, bipolar disorder, and migraine prophylaxis. The extended-release formulation allows for once-daily dosing, improving patient compliance by maintaining steady plasma drug concentrations over an extended period.
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Mechanistically, divalproex increases gamma-aminobutyric acid (GABA) levels in the brain, enhancing inhibitory neurotransmission and stabilizing neuronal activity. This action helps in controlling seizures, stabilizing mood swings, and reducing the frequency of migraine attacks. Grazirate OD 250 is indicated for the treatment of generalized and partial seizures, acute manic episodes associated with bipolar disorder, and prevention of migraine headaches.
It is contraindicated in patients with known hypersensitivity to divalproex or valproic acid and those with significant hepatic dysfunction. Common adverse effects include gastrointestinal disturbances, tremor, weight gain, and somnolence. Regular monitoring of liver function tests and blood counts is recommended during therapy. Dose adjustments may be necessary based on clinical response and tolerability.
Grazirate OD 250 should be used under medical supervision to ensure optimal therapeutic outcomes.
Dosage & How to Use
How to use Grazirate Tablet ER Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Grazirate OD 250 Tablet ER may be taken with or without food, but it is better to take it at a fixed time.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
Grazirate OD 250 Tablet ER may cause excessive drowsiness with alcohol.
High Risk
Pregnancy
Grazirate OD 250 Tablet ER is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Medical Advice
Driving
Grazirate OD 250 Tablet ER may cause side effects which could affect your ability to drive.
Exercise Caution
Liver
Grazirate OD 250 Tablet ER is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Regular Checkup
Breastfeeding
Grazirate OD 250 Tablet ER should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Consult Doctor
Kidney
Grazirate OD 250 Tablet ER is safe to use in patients with kidney disease. No dose adjustment of Grazirate OD 250 Tablet ER is recommended.
Regular Checkup
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