Grandem Syrup
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Bottle of 10 ml • SyrupPrescription requiredSchedule H
Grandem Syrup
Granisetron (1mg/5ml)
₹55.31
Bottle of 10 ml • Syrup
A valid prescription is required for this medicine.
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Active composition
Granisetron
How It Works
Granisetron antagonizes 5-HT3 serotonin receptors, preventing the stimulation of the vomiting center in the brain.
Uses & Benefits
Medical applications
HeadacheNausea
Grandem Syrup contains Granisetron at a concentration of 1mg per 5ml and is indicated for the prevention and treatment of nausea and vomiting associated with chemotherapy, radiotherapy, and postoperative conditions. Granisetron is a selective 5-HT3 receptor antagonist that works by blocking serotonin receptors located on vagal nerve terminals and in the central nervous system, thereby inhibiting the emetic signals responsible for triggering nausea and vomiting.
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This syrup formulation allows for ease of administration, particularly in pediatric and geriatric patients or those who have difficulty swallowing tablets. The onset of action is rapid, typically within one hour, providing effective symptomatic relief. Grandem Syrup should be administered as directed by a healthcare professional, with dosage adjusted according to the patient’s age, weight, and clinical condition.
Common adverse effects may include headache, constipation, and dizziness, though the medication is generally well tolerated. Caution is advised in patients with hepatic impairment, and it is contraindicated in individuals with known hypersensitivity to Granisetron or any of the syrup’s excipients. As with all antiemetics, it is essential to monitor for potential drug interactions and use under medical supervision to ensure safety and efficacy.
Dosage & How to Use
How to use Grandem Syrup Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Grandem Syrup may be taken with or without food, but it is better to take it at a fixed time.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
It is not known whether it is safe to consume alcohol with Grandem Syrup. Please consult your doctor.
High Risk
Pregnancy
Grandem Syrup is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Medical Advice
Driving
Grandem Syrup does not usually affect your ability to drive.
Exercise Caution
Liver
Grandem Syrup is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Grandem Syrup may not be needed in these patients. Please consult your doctor.
Regular Checkup
Breastfeeding
Grandem Syrup is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Consult Doctor
Kidney
Grandem Syrup is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Grandem Syrup may not be needed in these patients. Please consult your doctor.
Regular Checkup
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