
Pantoprazole (40mg) + Domperidone (30mg)
Active composition
+1 more active ingredient
Pantoprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, leading to decreased gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
GR8-OD Capsule PR is a combination pharmaceutical formulation containing Domperidone 30 mg and Pantoprazole 40 mg, designed for the management of gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating associated with delayed gastric emptying and gastroparesis. Pantoprazole, a proton pump inhibitor, suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, providing effective relief from acid-related disorders including gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcers. The combination of these agents offers a synergistic approach by addressing both impaired motility and excessive acid secretion, enhancing therapeutic outcomes in patients with upper gastrointestinal tract conditions. GR8-OD Capsule PR is typically administered orally, with dosing tailored according to clinical presentation and physician guidance. It is generally well-tolerated; however, potential adverse effects may include headache, dry mouth, abdominal cramps, and, rarely, extrapyramidal symptoms due to Domperidone. Caution is advised in patients with cardiac arrhythmias or electrolyte imbalances. This combination therapy should be used under medical supervision to ensure optimal efficacy and safety.
How to use GR8 Capsule PR Use it as advised by your doctor or check the label for directions before use. GR8 -OD Capsule PR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with GR8 -OD Capsule PR. Please consult your doctor.
High Risk
GR8 -OD Capsule PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
GR8 -OD Capsule PR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
GR8 -OD Capsule PR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of GR8 -OD Capsule PR may not be needed in these patients. Please consult your doctor.
Regular Checkup
GR8 -OD Capsule PR should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Consult Doctor
GR8 -OD Capsule PR should be used with caution in patients with kidney disease. Dose adjustment of GR8 -OD Capsule PR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for GR8 -OD Capsule PR

Domperidone (30mg) + Pantoprazole (40mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Pantoprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, leading to decreased gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
GR8-OD Capsule PR is a combination pharmaceutical formulation containing Domperidone 30 mg and Pantoprazole 40 mg, designed for the management of gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating associated with delayed gastric emptying and gastroparesis. Pantoprazole, a proton pump inhibitor, suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, providing effective relief from acid-related disorders including gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcers. The combination of these agents offers a synergistic approach by addressing both impaired motility and excessive acid secretion, enhancing therapeutic outcomes in patients with upper gastrointestinal tract conditions. GR8-OD Capsule PR is typically administered orally, with dosing tailored according to clinical presentation and physician guidance. It is generally well-tolerated; however, potential adverse effects may include headache, dry mouth, abdominal cramps, and, rarely, extrapyramidal symptoms due to Domperidone. Caution is advised in patients with cardiac arrhythmias or electrolyte imbalances. This combination therapy should be used under medical supervision to ensure optimal efficacy and safety.
How to use GR8 Capsule PR Use it as advised by your doctor or check the label for directions before use. GR8 -OD Capsule PR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with GR8 -OD Capsule PR. Please consult your doctor.
High Risk
GR8 -OD Capsule PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
GR8 -OD Capsule PR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
GR8 -OD Capsule PR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of GR8 -OD Capsule PR may not be needed in these patients. Please consult your doctor.
Regular Checkup
GR8 -OD Capsule PR should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Consult Doctor
GR8 -OD Capsule PR should be used with caution in patients with kidney disease. Dose adjustment of GR8 -OD Capsule PR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for GR8 -OD Capsule PR















