Gonablok 50 Capsule
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Danazol (50mg)
Box of 30 capsules • Capsule
A valid prescription is required for this medicine.
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Active composition
Danazol inhibits gonadotropin release, leading to decreased ovarian hormone production and suppression of endometrial tissue growth.
Medical applications
Gonablok 50 Capsule contains Danazol 50 mg, a synthetic steroid derivative with anti-gonadotropic and weak androgenic properties. It is primarily indicated for the management of endometriosis, fibrocystic breast disease, and hereditary angioedema. Danazol exerts its therapeutic effects by inhibiting the mid-cycle surge of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby suppressing ovarian steroidogenesis and reducing estrogen production.
This hormonal modulation leads to the regression of ectopic endometrial tissue and alleviation of associated symptoms such as pelvic pain and dysmenorrhea. Additionally, Danazol stabilizes vascular permeability in hereditary angioedema, reducing the frequency and severity of angioedema attacks. Gonablok 50 Capsule is administered orally, with dosage and duration tailored to the specific condition and patient response.
Common adverse effects include weight gain, acne, hirsutism, voice changes, and menstrual irregularities, attributed to its androgenic activity. It is contraindicated in pregnancy, lactation, hepatic dysfunction, and androgen-dependent tumors. Regular monitoring of liver function tests and lipid profiles is recommended during therapy. Gonablok 50 Capsule should be prescribed and used under strict medical supervision to ensure efficacy and minimize potential risks.
How to use Gonablok Capsule Take this medicine in the dose and duration as advised by your doctor. Gonablok 50 Capsule may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
It is unsafe to consume alcohol with Gonablok 50 Capsule.
High Risk
Gonablok 50 Capsule is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Medical Advice
Gonablok 50 Capsule may cause side effects which could affect your ability to drive. Gonablok 50 Capsule may cause some side effects such as dizziness, a spinning feeling, and changes in eyesight. This may affect your driving ability.
Exercise Caution
Gonablok 50 Capsule should be used with caution in patients with liver disease. Dose adjustment of Gonablok 50 Capsule may be needed. Please consult your doctor. Use of Gonablok 50 Capsule is not recommended in patients with the severe liver disease. Regular monitoring of liver function tests is advised while you are taking this medicine.
Regular Checkup
Gonablok 50 Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Gonablok 50 Capsule should be used with caution in patients with kidney disease. Dose adjustment of Gonablok 50 Capsule may be needed. Please consult your doctor. Use of Gonablok 50 Capsule may not be advised in patients with severe kidney disease.
Regular Checkup
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