Glivec 400mg Tablet
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Strip of 10 tablets • TabletPrescription requiredSchedule H
Glivec 400mg Tablet
Imatinib mesylate (400mg)
₹2235.63
Strip of 10 tablets • Tablet
A valid prescription is required for this medicine.
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Active composition
Imatinib mesylate 400 mg
Medicine Strength
400 mg
Uses & Benefits
Medical applications
Nausea
Glivec 400mg Tablet contains Imatinib mesylate, a selective tyrosine kinase inhibitor used primarily in the treatment of certain types of cancer. It is indicated for the management of chronic myeloid leukemia (CML), Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL), gastrointestinal stromal tumors (GIST), and other malignancies characterized by specific tyrosine kinase abnormalities.
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Imatinib mesylate functions by inhibiting the BCR-ABL tyrosine kinase enzyme, which is produced by the Philadelphia chromosome abnormality in CML, thereby preventing the proliferation of malignant cells. Additionally, it targets other tyrosine kinases such as c-KIT and PDGF receptors involved in GIST pathogenesis. Glivec is administered orally, and the dosage is determined based on the specific indication and patient response.
Common adverse effects include edema, nausea, muscle cramps, rash, and fatigue, while serious side effects may involve myelosuppression, hepatotoxicity, and cardiotoxicity, necessitating regular monitoring of blood counts and liver function tests during therapy. Glivec should be used under strict medical supervision, with attention to potential drug interactions and contraindications.
Patient adherence to prescribed dosing schedules is critical to achieving optimal therapeutic outcomes in the management of tyrosine kinase-driven malignancies.
Dosage & How to Use
How to use Glivec Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glivec 400mg Tablet is to be taken with food.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
It is not known whether it is safe to consume alcohol with Glivec 400mg Tablet. Please consult your doctor.
High Risk
Pregnancy
Glivec 400mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Medical Advice
Driving
Glivec 400mg Tablet may cause side effects which could affect your ability to drive.
Exercise Caution
Liver
Glivec 400mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Glivec 400mg Tablet may be needed. Please consult your doctor.
Regular Checkup
Breastfeeding
Glivec 400mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Lactating women should not breastfeed while using this drug and 15 days after stopping it.
Consult Doctor
Kidney
Glivec 400mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Glivec 400mg Tablet may be needed. Please consult your doctor.
Regular Checkup
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