Glioz 100 Capsule
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Bottle of 5 capsules • CapsulePrescription requiredSchedule H
Glioz 100 Capsule
Temozolomide (100mg)
₹7534.90
Bottle of 5 capsules • Capsule
A valid prescription is required for this medicine.
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Active composition
Temozolomide 100 mg
How It Works
Temozolomide methylates DNA, leading to the formation of DNA cross-links and inhibiting tumor cell proliferation.
Medicine Strength
100 mg
Uses & Benefits
Medical applications
InfectionNausea
Glioz 100 Capsule contains Temozolomide 100 mg, an oral alkylating agent primarily indicated for the treatment of certain types of brain tumors, including glioblastoma multiforme and anaplastic astrocytoma. Temozolomide exerts its antineoplastic effect by methylating DNA at the O6 and N7 positions of guanine residues, leading to DNA strand breaks and apoptosis in rapidly dividing tumor cells.
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Glioz 100 is typically administered as part of a chemotherapy regimen either concomitantly with radiotherapy or as maintenance therapy following initial treatment. The capsule formulation allows for convenient oral administration, improving patient compliance. Dosage and treatment schedules should be individualized based on patient weight, hematologic status, and overall clinical condition, with regular monitoring of blood counts due to the risk of myelosuppression, including neutropenia and thrombocytopenia.
Common adverse effects include nausea, vomiting, fatigue, and hematologic toxicities, while rare but serious complications such as opportunistic infections and hepatotoxicity may occur. Glioz 100 should be used under strict medical supervision, with appropriate supportive care measures and periodic laboratory evaluations to optimize therapeutic outcomes and minimize toxicity. It is contraindicated in patients with known hypersensitivity to Temozolomide or other alkylating agents.
Dosage & How to Use
Dacarbazine Derivative
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
Glioz 100 Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
High Risk
Pregnancy
Glioz 100 Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Medical Advice
Driving
Glioz 100 Capsule is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Glioz 100 Capsule may not be needed in these patients. Please consult your doctor. Cautious use is advised in patients with severe kidney disease while they are taking Glioz 100 Capsule.
Exercise Caution
Breastfeeding
Glioz 100 Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
Kidney
Glioz 100 Capsule should be used with caution in patients with severe liver disease. Dose adjustment of Glioz 100 Capsule may be needed. Please consult your doctor. Limited information is available on the use of Glioz 100 Capsule in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
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