
Gabapentin (400mg) + Nortriptyline (10mg)
Active composition
+1 more active ingredient
Gabapentin binds to the alpha-2-delta subunit of voltage-gated calcium channels, inhibiting excitatory neurotransmitter release and reducing neuronal excitability.
Nortriptyline inhibits the reuptake of norepinephrine and serotonin, increasing their levels in the synaptic cleft and enhancing mood.
Medical applications
Giant-NT Tablet is a combination pharmaceutical formulation containing Gabapentin 400 mg and Nortriptyline 10 mg, indicated primarily for the management of neuropathic pain and certain types of chronic pain disorders. Gabapentin, an anticonvulsant agent, modulates neuronal excitability by binding to the α2δ subunit of voltage-gated calcium channels, thereby reducing neurotransmitter release and alleviating neuropathic pain symptoms. Nortriptyline, a tricyclic antidepressant, inhibits the reuptake of norepinephrine and serotonin, enhancing descending inhibitory pain pathways and providing analgesic effects. The synergistic action of these two active ingredients offers improved efficacy in pain control compared to monotherapy. Giant-NT is prescribed for conditions such as diabetic neuropathy, postherpetic neuralgia, and other neuropathic pain syndromes. Dosage should be individualized based on patient response and tolerability, with careful titration to minimize adverse effects. Common side effects may include dizziness, somnolence, dry mouth, and gastrointestinal disturbances. Caution is advised in patients with a history of cardiac arrhythmias, glaucoma, or renal impairment. This medication should be used under strict medical supervision, and abrupt discontinuation should be avoided to prevent withdrawal symptoms. Giant-NT Tablet provides an effective therapeutic option for patients requiring combined neuropathic pain management.
How to use Giant-NT Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Giant-NT Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Giant-NT Tablet may cause excessive drowsiness with alcohol.
High Risk
Giant-NT Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Giant-NT Tablet may cause side effects which could affect your ability to drive. As Giant-NT Tablet may affect your alertness which may affect your ability to drive.
Exercise Caution
Giant-NT Tablet should be used with caution in patients with liver disease. Dose adjustment of Giant-NT Tablet may be needed. Please consult your doctor. Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine. Use of Giant-NT Tablet is not recommended in patients with severe liver disease.
Regular Checkup
Giant-NT Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Giant-NT Tablet should be used with caution in patients with kidney disease. Dose adjustment of Giant-NT Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Giant-NT Tablet

Gabapentin (400mg) + Nortriptyline (10mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Gabapentin binds to the alpha-2-delta subunit of voltage-gated calcium channels, inhibiting excitatory neurotransmitter release and reducing neuronal excitability.
Nortriptyline inhibits the reuptake of norepinephrine and serotonin, increasing their levels in the synaptic cleft and enhancing mood.
Medical applications
Giant-NT Tablet is a combination pharmaceutical formulation containing Gabapentin 400 mg and Nortriptyline 10 mg, indicated primarily for the management of neuropathic pain and certain types of chronic pain disorders. Gabapentin, an anticonvulsant agent, modulates neuronal excitability by binding to the α2δ subunit of voltage-gated calcium channels, thereby reducing neurotransmitter release and alleviating neuropathic pain symptoms. Nortriptyline, a tricyclic antidepressant, inhibits the reuptake of norepinephrine and serotonin, enhancing descending inhibitory pain pathways and providing analgesic effects. The synergistic action of these two active ingredients offers improved efficacy in pain control compared to monotherapy. Giant-NT is prescribed for conditions such as diabetic neuropathy, postherpetic neuralgia, and other neuropathic pain syndromes. Dosage should be individualized based on patient response and tolerability, with careful titration to minimize adverse effects. Common side effects may include dizziness, somnolence, dry mouth, and gastrointestinal disturbances. Caution is advised in patients with a history of cardiac arrhythmias, glaucoma, or renal impairment. This medication should be used under strict medical supervision, and abrupt discontinuation should be avoided to prevent withdrawal symptoms. Giant-NT Tablet provides an effective therapeutic option for patients requiring combined neuropathic pain management.
How to use Giant-NT Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Giant-NT Tablet may be taken with or without food, but it is better to take it at a fixed time.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Giant-NT Tablet may cause excessive drowsiness with alcohol.
High Risk
Giant-NT Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Giant-NT Tablet may cause side effects which could affect your ability to drive. As Giant-NT Tablet may affect your alertness which may affect your ability to drive.
Exercise Caution
Giant-NT Tablet should be used with caution in patients with liver disease. Dose adjustment of Giant-NT Tablet may be needed. Please consult your doctor. Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine. Use of Giant-NT Tablet is not recommended in patients with severe liver disease.
Regular Checkup
Giant-NT Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Giant-NT Tablet should be used with caution in patients with kidney disease. Dose adjustment of Giant-NT Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Giant-NT Tablet















