Gestrin-DSR Capsule
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1 units • OtherPrescription requiredSchedule H
Gestrin-DSR Capsule
Domperidone (30mg) + Rabeprazole (20mg)
₹120.00
1 units • Other
A valid prescription is required for this medicine.
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Active composition
Rabeprazole 20 mg
+1 more active ingredient
How It Works
Rabeprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medicine Strength
20 mg
All Active Ingredients
Rabeprazole20 mg
Domperidone30 mg
Uses & Benefits
Medical applications
FluUlcerNausea
Gestrin-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30 mg and Rabeprazole 20 mg, designed to manage gastrointestinal disorders characterized by acid-related symptoms and motility disturbances. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility by increasing the tone of the lower esophageal sphincter and accelerating gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating.
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Rabeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, providing effective relief from acid-related conditions including gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcers. The synergistic action of these agents in Gestrin-DSR Capsule offers comprehensive management of upper gastrointestinal symptoms by addressing both acid hypersecretion and impaired gastric motility.
This combination is particularly beneficial in patients with refractory GERD or functional dyspepsia where monotherapy may be insufficient. Gestrin-DSR should be administered as prescribed by a healthcare professional, with consideration of contraindications such as known hypersensitivity to either component, and caution in patients with cardiac arrhythmias or electrolyte imbalances.
Regular monitoring is advised to ensure therapeutic efficacy and minimize potential adverse effects.
Dosage & How to Use
How to use Gestrin-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gestrin-DSR Capsule is to be taken empty stomach.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
Caution is advised when consuming alcohol with Gestrin-DSR Capsule. Please consult your doctor.
High Risk
Pregnancy
Gestrin-DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Driving
Gestrin-DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Liver
Gestrin-DSR Capsule should be used with caution in patients with liver disease. Dose adjustment of Gestrin-DSR Capsule may be needed. Please consult your doctor. Use of Gestrin-DSR Capsule is not recommended in patients with moderate and severe liver disease.
Regular Checkup
Breastfeeding
Gestrin-DSR Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Consult Doctor
Kidney
Gestrin-DSR Capsule should be used with caution in patients with kidney disease. Dose adjustment of Gestrin-DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
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