Gastroprazole D Capsule
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Domperidone (10mg) + Omeprazole (20mg)
Strip of 15 capsules • Capsule
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Omeprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, leading to decreased gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Gastroprazole D Capsule is a combination pharmaceutical formulation containing Domperidone 10 mg and Omeprazole 20 mg, designed for the management of gastrointestinal disorders associated with acid reflux and motility disturbances. Omeprazole, a proton pump inhibitor, effectively suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, thereby providing symptomatic relief and promoting healing of acid-related mucosal damage.
Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility and accelerates gastric emptying, reducing symptoms such as nausea, vomiting, bloating, and discomfort associated with delayed gastric emptying or gastroparesis. The synergistic action of these two agents makes Gastroprazole D Capsule particularly useful in treating gastroesophageal reflux disease (GERD), functional dyspepsia, and other related upper gastrointestinal motility disorders.
It is generally well tolerated; however, caution is advised in patients with cardiac arrhythmias or electrolyte imbalances due to Domperidone’s potential to prolong the QT interval. Gastroprazole D should be administered as prescribed by a healthcare professional, with adherence to recommended dosage and duration to optimize therapeutic outcomes and minimize adverse effects.
How to use Gastroprazole D Capsule Take this medicine in the dose and duration as advised by your doctor. Gastroprazole D Capsule is to be taken empty stomach.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Caution is advised when consuming alcohol with Gastroprazole D Capsule. Please consult your doctor.
High Risk
Gastroprazole D Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Gastroprazole D Capsule may cause side effects which could affect your ability to drive. Gastroprazole D Capsule may cause dizziness and visual disturbances. This may affect your driving ability.
Exercise Caution
Gastroprazole D Capsule should be used with caution in patients with liver disease. Dose adjustment of Gastroprazole D Capsule may be needed. Please consult your doctor. Use of Gastroprazole D Capsule is not recommended in patients with moderate and severe liver disease.
Regular Checkup
Gastroprazole D Capsule is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Consult Doctor
Gastroprazole D Capsule should be used with caution in patients with kidney disease. Dose adjustment of Gastroprazole D Capsule may be needed. Please consult your doctor.
Regular Checkup
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