
Pantoprazole (40mg) + Domperidone (10mg)
Active composition
+1 more active ingredient
Pantoprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, leading to decreased gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Gastopan-D Tablet is a combination medication containing Domperidone 10 mg and Pantoprazole 40 mg, formulated to manage gastrointestinal disorders characterized by acid reflux, indigestion, and delayed gastric emptying. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating. Pantoprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, providing effective relief from acid-related conditions including gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcers. The synergistic action of these two agents addresses both the symptomatic relief of gastric motility disorders and the reduction of gastric acidity, promoting mucosal healing and symptom resolution. Gastopan-D is indicated for patients experiencing dyspepsia, GERD, and functional dyspepsia with associated delayed gastric emptying. It is generally well-tolerated; however, caution is advised in patients with underlying cardiac conditions due to the potential risk of QT interval prolongation associated with Domperidone. Use should be under medical supervision, with dosage adjustments based on clinical response and patient tolerance. This combination therapy offers a comprehensive approach to managing complex upper gastrointestinal symptoms.
How to use Gastopan-D Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gastopan-D Tablet is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Gastopan-D Tablet. Please consult your doctor.
High Risk
Gastopan-D Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Gastopan-D Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Gastopan-D Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Gastopan-D Tablet may not be needed in these patients. Please consult your doctor.
Regular Checkup
Gastopan-D Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Consult Doctor
Gastopan-D Tablet should be used with caution in patients with kidney disease. Dose adjustment of Gastopan-D Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Gastopan-D Tablet

Domperidone (10mg) + Pantoprazole (40mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Pantoprazole irreversibly inhibits the H+/K+ ATPase enzyme in gastric parietal cells, leading to decreased gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Gastopan-D Tablet is a combination medication containing Domperidone 10 mg and Pantoprazole 40 mg, formulated to manage gastrointestinal disorders characterized by acid reflux, indigestion, and delayed gastric emptying. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating. Pantoprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, providing effective relief from acid-related conditions including gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcers. The synergistic action of these two agents addresses both the symptomatic relief of gastric motility disorders and the reduction of gastric acidity, promoting mucosal healing and symptom resolution. Gastopan-D is indicated for patients experiencing dyspepsia, GERD, and functional dyspepsia with associated delayed gastric emptying. It is generally well-tolerated; however, caution is advised in patients with underlying cardiac conditions due to the potential risk of QT interval prolongation associated with Domperidone. Use should be under medical supervision, with dosage adjustments based on clinical response and patient tolerance. This combination therapy offers a comprehensive approach to managing complex upper gastrointestinal symptoms.
How to use Gastopan-D Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gastopan-D Tablet is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Gastopan-D Tablet. Please consult your doctor.
High Risk
Gastopan-D Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Gastopan-D Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Gastopan-D Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Gastopan-D Tablet may not be needed in these patients. Please consult your doctor.
Regular Checkup
Gastopan-D Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Consult Doctor
Gastopan-D Tablet should be used with caution in patients with kidney disease. Dose adjustment of Gastopan-D Tablet may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Gastopan-D Tablet















