
Clobetasol (0.05% w/w) + Neomycin (0.5% w/w) + Miconazole (2% w/w) + Chlorocresol (0.1% w/w)
Active composition
+3 more active ingredients
Clobetasol binds to glucocorticoid receptors, inhibiting the transcription of pro-inflammatory genes and reducing inflammation.
Neomycin binds to the 30S ribosomal subunit of bacteria, inhibiting protein synthesis and leading to bacterial cell death.
Miconazole inhibits the synthesis of ergosterol, compromising fungal cell membrane integrity and leading to cell death.
Medical applications
Four Derm AF Cream is a potent topical formulation combining Clobetasol (0.05% w/w), Neomycin (0.5% w/w), Miconazole (2% w/w), and Chlorocresol (0.1% w/w) designed to effectively manage a variety of dermatological conditions. Clobetasol, a highly potent corticosteroid, provides strong anti-inflammatory, antipruritic, and vasoconstrictive effects, helping to reduce redness, swelling, and itching associated with inflammatory skin disorders. Neomycin, an aminoglycoside antibiotic, targets and inhibits the growth of susceptible bacteria, preventing or treating secondary bacterial infections. Miconazole, an imidazole antifungal agent, combats fungal infections by disrupting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby treating conditions like athlete’s foot, ringworm, and candidiasis. Chlorocresol acts as a preservative with antimicrobial properties, ensuring the cream remains free from microbial contamination during use. Four Derm AF Cream is indicated for mixed infections involving bacteria and fungi, especially where inflammation is prominent. It should be applied as directed by a healthcare professional, typically in a thin layer on the affected area. Caution is advised in prolonged use due to potential side effects of corticosteroids, and it is contraindicated in viral infections and hypersensitivity to any components. This combination therapy offers comprehensive relief by addressing inflammation, bacterial, and fungal infections simultaneously.
How to use Four Derm AF Cream This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
No interaction found/established
High Risk
Four Derm AF Cream may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
No interaction found/established
Exercise Caution
No interaction found/established
Regular Checkup
Information regarding the use of Four Derm AF Cream during breastfeeding is not available. Please consult your doctor.
Consult Doctor
No interaction found/established
Regular Checkup
0 reviews for Four Derm AF Cream

Clobetasol (0.05% w/w) + Neomycin (0.5% w/w) + Miconazole (2% w/w) + Chlorocresol (0.1% w/w)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+3 more active ingredients
Clobetasol binds to glucocorticoid receptors, inhibiting the transcription of pro-inflammatory genes and reducing inflammation.
Neomycin binds to the 30S ribosomal subunit of bacteria, inhibiting protein synthesis and leading to bacterial cell death.
Miconazole inhibits the synthesis of ergosterol, compromising fungal cell membrane integrity and leading to cell death.
Medical applications
Four Derm AF Cream is a potent topical formulation combining Clobetasol (0.05% w/w), Neomycin (0.5% w/w), Miconazole (2% w/w), and Chlorocresol (0.1% w/w) designed to effectively manage a variety of dermatological conditions. Clobetasol, a highly potent corticosteroid, provides strong anti-inflammatory, antipruritic, and vasoconstrictive effects, helping to reduce redness, swelling, and itching associated with inflammatory skin disorders. Neomycin, an aminoglycoside antibiotic, targets and inhibits the growth of susceptible bacteria, preventing or treating secondary bacterial infections. Miconazole, an imidazole antifungal agent, combats fungal infections by disrupting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby treating conditions like athlete’s foot, ringworm, and candidiasis. Chlorocresol acts as a preservative with antimicrobial properties, ensuring the cream remains free from microbial contamination during use. Four Derm AF Cream is indicated for mixed infections involving bacteria and fungi, especially where inflammation is prominent. It should be applied as directed by a healthcare professional, typically in a thin layer on the affected area. Caution is advised in prolonged use due to potential side effects of corticosteroids, and it is contraindicated in viral infections and hypersensitivity to any components. This combination therapy offers comprehensive relief by addressing inflammation, bacterial, and fungal infections simultaneously.
How to use Four Derm AF Cream This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
No interaction found/established
High Risk
Four Derm AF Cream may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
No interaction found/established
Exercise Caution
No interaction found/established
Regular Checkup
Information regarding the use of Four Derm AF Cream during breastfeeding is not available. Please consult your doctor.
Consult Doctor
No interaction found/established
Regular Checkup
0 reviews for Four Derm AF Cream















