
Esomeprazole (40mg) + Domperidone (30mg)
Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Esopraid D Capsule SR is a combination pharmaceutical formulation containing Domperidone 30 mg and Esomeprazole 40 mg, designed for the management of gastroesophageal reflux disease (GERD), acid reflux, and related upper gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility by increasing the tone of the lower esophageal sphincter and accelerating gastric emptying, thereby reducing symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor (PPI), selectively inhibits the H+/K+ ATPase enzyme system in the gastric parietal cells, leading to a significant and prolonged reduction in gastric acid secretion. The sustained-release (SR) formulation ensures a gradual and consistent release of active ingredients, optimizing therapeutic efficacy and improving patient compliance. Esopraid D Capsule SR is indicated for patients with erosive esophagitis, non-erosive reflux disease, and Zollinger-Ellison syndrome, as well as for the prevention of acid-related damage to the esophageal mucosa. It should be used under medical supervision, with caution advised in patients with hepatic impairment or known hypersensitivity to its components. Common adverse effects may include headache, dry mouth, and gastrointestinal disturbances. This combination therapy offers a dual mechanism approach, addressing both acid suppression and motility enhancement for comprehensive symptom relief.
How to use Esopraid D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esopraid D Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Esopraid D Capsule SR. Please consult your doctor.
High Risk
Esopraid D Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Esopraid D Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Esopraid D Capsule SR is safe to use in patients with liver disease. No dose adjustment of Esopraid D Capsule SR is recommended.
Regular Checkup
Esopraid D Capsule SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Esopraid D Capsule SR should be used with caution in patients with severe kidney disease. Dose adjustment of Esopraid D Capsule SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Esopraid D Capsule SR

Domperidone (30mg) + Esomeprazole (40mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Esopraid D Capsule SR is a combination pharmaceutical formulation containing Domperidone 30 mg and Esomeprazole 40 mg, designed for the management of gastroesophageal reflux disease (GERD), acid reflux, and related upper gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility by increasing the tone of the lower esophageal sphincter and accelerating gastric emptying, thereby reducing symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor (PPI), selectively inhibits the H+/K+ ATPase enzyme system in the gastric parietal cells, leading to a significant and prolonged reduction in gastric acid secretion. The sustained-release (SR) formulation ensures a gradual and consistent release of active ingredients, optimizing therapeutic efficacy and improving patient compliance. Esopraid D Capsule SR is indicated for patients with erosive esophagitis, non-erosive reflux disease, and Zollinger-Ellison syndrome, as well as for the prevention of acid-related damage to the esophageal mucosa. It should be used under medical supervision, with caution advised in patients with hepatic impairment or known hypersensitivity to its components. Common adverse effects may include headache, dry mouth, and gastrointestinal disturbances. This combination therapy offers a dual mechanism approach, addressing both acid suppression and motility enhancement for comprehensive symptom relief.
How to use Esopraid D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esopraid D Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Esopraid D Capsule SR. Please consult your doctor.
High Risk
Esopraid D Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Esopraid D Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Esopraid D Capsule SR is safe to use in patients with liver disease. No dose adjustment of Esopraid D Capsule SR is recommended.
Regular Checkup
Esopraid D Capsule SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Esopraid D Capsule SR should be used with caution in patients with severe kidney disease. Dose adjustment of Esopraid D Capsule SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Esopraid D Capsule SR















