
Domperidone (30mg) + Esomeprazole (40mg)
Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Medical applications
Esomefol-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30mg and Esomeprazole 40mg, indicated for the management of gastroesophageal reflux disease (GERD), dyspepsia, and related upper gastrointestinal disorders. Esomeprazole, a proton pump inhibitor, acts by selectively inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, thereby suppressing gastric acid secretion and promoting mucosal healing. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility by accelerating gastric emptying and increasing lower esophageal sphincter tone, which helps alleviate symptoms such as nausea, vomiting, and bloating. The synergistic action of these agents provides effective relief from acid-related symptoms and improves gastrointestinal motility, making Esomefol-DSR suitable for patients with acid reflux accompanied by delayed gastric emptying. The capsule should be administered as prescribed by a healthcare professional, typically before meals, to optimize therapeutic outcomes. Caution is advised in patients with known hypersensitivity to either component, cardiac arrhythmias, or hepatic impairment. Regular monitoring may be necessary during prolonged use. Esomefol-DSR offers a comprehensive approach to managing acid peptic disorders by combining acid suppression with prokinetic activity.
How to use Esomefol-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esomefol-DSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Esomefol-DSR Capsule. Please consult your doctor.
High Risk
Esomefol-DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Esomefol-DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Esomefol-DSR Capsule is safe to use in patients with liver disease. No dose adjustment of Esomefol-DSR Capsule is recommended.
Regular Checkup
Esomefol-DSR Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Esomefol-DSR Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Esomefol-DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Esomefol-DSR Capsule

Domperidone (30mg) + Esomeprazole (40mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Medical applications
Esomefol-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30mg and Esomeprazole 40mg, indicated for the management of gastroesophageal reflux disease (GERD), dyspepsia, and related upper gastrointestinal disorders. Esomeprazole, a proton pump inhibitor, acts by selectively inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, thereby suppressing gastric acid secretion and promoting mucosal healing. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility by accelerating gastric emptying and increasing lower esophageal sphincter tone, which helps alleviate symptoms such as nausea, vomiting, and bloating. The synergistic action of these agents provides effective relief from acid-related symptoms and improves gastrointestinal motility, making Esomefol-DSR suitable for patients with acid reflux accompanied by delayed gastric emptying. The capsule should be administered as prescribed by a healthcare professional, typically before meals, to optimize therapeutic outcomes. Caution is advised in patients with known hypersensitivity to either component, cardiac arrhythmias, or hepatic impairment. Regular monitoring may be necessary during prolonged use. Esomefol-DSR offers a comprehensive approach to managing acid peptic disorders by combining acid suppression with prokinetic activity.
How to use Esomefol-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esomefol-DSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Esomefol-DSR Capsule. Please consult your doctor.
High Risk
Esomefol-DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Esomefol-DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Esomefol-DSR Capsule is safe to use in patients with liver disease. No dose adjustment of Esomefol-DSR Capsule is recommended.
Regular Checkup
Esomefol-DSR Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Esomefol-DSR Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Esomefol-DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Esomefol-DSR Capsule















