
Esomeprazole (40mg) + Domperidone (30mg)
Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Esolyst-D Capsule SR is a combination medication containing Domperidone 30mg and Esomeprazole 40mg, formulated to provide sustained relief from gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, bloating, and discomfort associated with delayed gastric emptying. Esomeprazole, a proton pump inhibitor, suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, effectively reducing acid-related damage and promoting mucosal healing. This synergistic combination is indicated for the management of gastroesophageal reflux disease (GERD), erosive esophagitis, peptic ulcers, and functional dyspepsia, particularly when accompanied by motility disturbances. Esolyst-D Capsule SR is designed for sustained release, ensuring prolonged therapeutic plasma concentrations and improved patient compliance. It should be administered as prescribed, typically before meals, and is contraindicated in patients with known hypersensitivity to its components, prolactinoma, or gastrointestinal hemorrhage. Caution is advised in patients with hepatic impairment or cardiac arrhythmias. Common adverse effects may include headache, dry mouth, and abdominal discomfort. Consultation with a healthcare professional is recommended prior to initiation to optimize treatment outcomes and monitor for potential drug interactions.
How to use Esolyst-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esolyst-D Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Esolyst-D Capsule SR. Please consult your doctor.
High Risk
Esolyst-D Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Esolyst-D Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Esolyst-D Capsule SR is safe to use in patients with liver disease. No dose adjustment of Esolyst-D Capsule SR is recommended.
Regular Checkup
Esolyst-D Capsule SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Esolyst-D Capsule SR should be used with caution in patients with severe kidney disease. Dose adjustment of Esolyst-D Capsule SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Esolyst-D Capsule SR

Domperidone (30mg) + Esomeprazole (40mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Esolyst-D Capsule SR is a combination medication containing Domperidone 30mg and Esomeprazole 40mg, formulated to provide sustained relief from gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, bloating, and discomfort associated with delayed gastric emptying. Esomeprazole, a proton pump inhibitor, suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, effectively reducing acid-related damage and promoting mucosal healing. This synergistic combination is indicated for the management of gastroesophageal reflux disease (GERD), erosive esophagitis, peptic ulcers, and functional dyspepsia, particularly when accompanied by motility disturbances. Esolyst-D Capsule SR is designed for sustained release, ensuring prolonged therapeutic plasma concentrations and improved patient compliance. It should be administered as prescribed, typically before meals, and is contraindicated in patients with known hypersensitivity to its components, prolactinoma, or gastrointestinal hemorrhage. Caution is advised in patients with hepatic impairment or cardiac arrhythmias. Common adverse effects may include headache, dry mouth, and abdominal discomfort. Consultation with a healthcare professional is recommended prior to initiation to optimize treatment outcomes and monitor for potential drug interactions.
How to use Esolyst-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esolyst-D Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Esolyst-D Capsule SR. Please consult your doctor.
High Risk
Esolyst-D Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Esolyst-D Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Esolyst-D Capsule SR is safe to use in patients with liver disease. No dose adjustment of Esolyst-D Capsule SR is recommended.
Regular Checkup
Esolyst-D Capsule SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Esolyst-D Capsule SR should be used with caution in patients with severe kidney disease. Dose adjustment of Esolyst-D Capsule SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Esolyst-D Capsule SR















