
Domperidone (30mg) + Esomeprazole (40mg)
Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Medical applications
Esokap-D Capsule SR is a combination pharmaceutical formulation containing Domperidone 30 mg and Esomeprazole 40 mg, designed for the management of gastroesophageal reflux disease (GERD), dyspepsia, and related upper gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility by enhancing gastric emptying and increasing lower esophageal sphincter tone, thereby reducing symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, promoting mucosal healing and symptom relief in acid-related conditions. The sustained-release (SR) formulation ensures prolonged therapeutic plasma concentrations, improving patient compliance and efficacy. Esokap-D Capsule SR is indicated for patients requiring both acid suppression and prokinetic therapy, particularly in cases where delayed gastric emptying contributes to symptomatology. It should be used under medical supervision, considering potential contraindications such as hypersensitivity to components, and caution in patients with cardiac arrhythmias or hepatic impairment. Common adverse effects may include headache, dry mouth, and abdominal discomfort. Drug interactions should be evaluated prior to initiation. Esokap-D Capsule SR offers a synergistic approach to managing upper gastrointestinal symptoms by addressing both acid secretion and motility dysfunction.
How to use Esokap-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esokap-D Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Esokap-D Capsule SR. Please consult your doctor.
High Risk
Esokap-D Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Esokap-D Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Esokap-D Capsule SR is safe to use in patients with liver disease. No dose adjustment of Esokap-D Capsule SR is recommended.
Regular Checkup
Esokap-D Capsule SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Esokap-D Capsule SR should be used with caution in patients with severe kidney disease. Dose adjustment of Esokap-D Capsule SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Esokap-D Capsule SR

Domperidone (30mg) + Esomeprazole (40mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Medical applications
Esokap-D Capsule SR is a combination pharmaceutical formulation containing Domperidone 30 mg and Esomeprazole 40 mg, designed for the management of gastroesophageal reflux disease (GERD), dyspepsia, and related upper gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility by enhancing gastric emptying and increasing lower esophageal sphincter tone, thereby reducing symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, promoting mucosal healing and symptom relief in acid-related conditions. The sustained-release (SR) formulation ensures prolonged therapeutic plasma concentrations, improving patient compliance and efficacy. Esokap-D Capsule SR is indicated for patients requiring both acid suppression and prokinetic therapy, particularly in cases where delayed gastric emptying contributes to symptomatology. It should be used under medical supervision, considering potential contraindications such as hypersensitivity to components, and caution in patients with cardiac arrhythmias or hepatic impairment. Common adverse effects may include headache, dry mouth, and abdominal discomfort. Drug interactions should be evaluated prior to initiation. Esokap-D Capsule SR offers a synergistic approach to managing upper gastrointestinal symptoms by addressing both acid secretion and motility dysfunction.
How to use Esokap-D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esokap-D Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Esokap-D Capsule SR. Please consult your doctor.
High Risk
Esokap-D Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Esokap-D Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Esokap-D Capsule SR is safe to use in patients with liver disease. No dose adjustment of Esokap-D Capsule SR is recommended.
Regular Checkup
Esokap-D Capsule SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Esokap-D Capsule SR should be used with caution in patients with severe kidney disease. Dose adjustment of Esokap-D Capsule SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Esokap-D Capsule SR















