
Esomeprazole (40mg) + Levosulpiride (75mg)
Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Medical applications
Esofly-L Capsule SR is a sustained-release formulation combining Levosulpiride 75 mg and Esomeprazole 40 mg, designed to manage gastrointestinal disorders effectively. Levosulpiride, a selective dopamine D2 receptor antagonist, facilitates gastrointestinal motility by enhancing gastric emptying and improving esophageal sphincter tone, making it beneficial in conditions such as functional dyspepsia, gastroesophageal reflux disease (GERD), and diabetic gastroparesis. Esomeprazole, a proton pump inhibitor, suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, thereby providing symptomatic relief and promoting mucosal healing in acid-related disorders. The combination therapy addresses both motility dysfunction and acid hypersecretion, offering comprehensive management of upper gastrointestinal symptoms including heartburn, regurgitation, and epigastric discomfort. The sustained-release mechanism ensures prolonged therapeutic plasma concentrations, enhancing patient compliance and clinical efficacy. Esofly-L Capsule SR should be administered as prescribed, typically before meals, and is contraindicated in patients with known hypersensitivity to its components. Caution is advised in individuals with hepatic or renal impairment. Potential adverse effects may include headache, dizziness, and gastrointestinal disturbances. Clinical monitoring is recommended to optimize treatment outcomes and minimize risks.
How to use Esofly-L Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esofly-L Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Esofly-L Capsule SR.
High Risk
Esofly-L Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Esofly-L Capsule SR may cause side effects which could affect your ability to drive. Esofly-L Capsule SR may cause drowsiness, numbness, or dyskinesias, therefore they should be advised to avoid driving and operations requiring supervision.
Exercise Caution
Esofly-L Capsule SR should be used with caution in patients with severe liver disease. Dose adjustment of Esofly-L Capsule SR may be needed. Please consult your doctor.
Regular Checkup
Information regarding the use of Esofly-L Capsule SR during breastfeeding is not available. Please consult your doctor.
Consult Doctor
There is limited information available on the use of Esofly-L Capsule SR in patients with kidney disease. Please consult your doctor. However, limited data suggest a cautious use of this medicine in these patients.
Regular Checkup
0 reviews for Esofly-L Capsule SR

Levosulpiride (75mg) + Esomeprazole (40mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Medical applications
Esofly-L Capsule SR is a sustained-release formulation combining Levosulpiride 75 mg and Esomeprazole 40 mg, designed to manage gastrointestinal disorders effectively. Levosulpiride, a selective dopamine D2 receptor antagonist, facilitates gastrointestinal motility by enhancing gastric emptying and improving esophageal sphincter tone, making it beneficial in conditions such as functional dyspepsia, gastroesophageal reflux disease (GERD), and diabetic gastroparesis. Esomeprazole, a proton pump inhibitor, suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, thereby providing symptomatic relief and promoting mucosal healing in acid-related disorders. The combination therapy addresses both motility dysfunction and acid hypersecretion, offering comprehensive management of upper gastrointestinal symptoms including heartburn, regurgitation, and epigastric discomfort. The sustained-release mechanism ensures prolonged therapeutic plasma concentrations, enhancing patient compliance and clinical efficacy. Esofly-L Capsule SR should be administered as prescribed, typically before meals, and is contraindicated in patients with known hypersensitivity to its components. Caution is advised in individuals with hepatic or renal impairment. Potential adverse effects may include headache, dizziness, and gastrointestinal disturbances. Clinical monitoring is recommended to optimize treatment outcomes and minimize risks.
How to use Esofly-L Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esofly-L Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Esofly-L Capsule SR.
High Risk
Esofly-L Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Esofly-L Capsule SR may cause side effects which could affect your ability to drive. Esofly-L Capsule SR may cause drowsiness, numbness, or dyskinesias, therefore they should be advised to avoid driving and operations requiring supervision.
Exercise Caution
Esofly-L Capsule SR should be used with caution in patients with severe liver disease. Dose adjustment of Esofly-L Capsule SR may be needed. Please consult your doctor.
Regular Checkup
Information regarding the use of Esofly-L Capsule SR during breastfeeding is not available. Please consult your doctor.
Consult Doctor
There is limited information available on the use of Esofly-L Capsule SR in patients with kidney disease. Please consult your doctor. However, limited data suggest a cautious use of this medicine in these patients.
Regular Checkup
0 reviews for Esofly-L Capsule SR















