
Levosulpiride (75mg) + Esomeprazole (40mg)
Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Medical applications
Esofine-LS Capsule SR is a combination pharmaceutical formulation containing Levosulpiride 75 mg and Esomeprazole 40 mg, designed for the management of gastrointestinal disorders. Levosulpiride, a selective dopamine D2 receptor antagonist, exhibits prokinetic and antiemetic properties by enhancing gastrointestinal motility and modulating central dopaminergic pathways. Esomeprazole, a proton pump inhibitor, effectively suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme in gastric parietal cells, thereby providing symptomatic relief and promoting mucosal healing in acid-related conditions. The sustained-release formulation ensures prolonged therapeutic plasma concentrations, optimizing efficacy and improving patient compliance. Esofine-LS Capsule SR is indicated for the treatment of gastroesophageal reflux disease (GERD), functional dyspepsia, gastritis, and associated motility disorders. It is particularly beneficial in patients presenting with symptoms such as heartburn, epigastric pain, nausea, and bloating. Administration should be as prescribed by a healthcare professional, with consideration for contraindications including hypersensitivity to either component, and caution in patients with renal or hepatic impairment. Common adverse effects may include headache, dizziness, and mild gastrointestinal disturbances. Regular monitoring and adherence to prescribed dosage are essential to maximize therapeutic outcomes and minimize potential risks.
How to use Esofine-LS Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esofine-LS Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Esofine-LS Capsule SR.
High Risk
Esofine-LS Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Esofine-LS Capsule SR may cause side effects which could affect your ability to drive. Esofine-LS Capsule SR may cause drowsiness, numbness, or dyskinesias, therefore they should be advised to avoid driving and operations requiring supervision.
Exercise Caution
Esofine-LS Capsule SR should be used with caution in patients with severe liver disease. Dose adjustment of Esofine-LS Capsule SR may be needed. Please consult your doctor.
Regular Checkup
Information regarding the use of Esofine-LS Capsule SR during breastfeeding is not available. Please consult your doctor.
Consult Doctor
There is limited information available on the use of Esofine-LS Capsule SR in patients with kidney disease. Please consult your doctor. However, limited data suggest a cautious use of this medicine in these patients.
Regular Checkup
0 reviews for Esofine-LS Capsule SR

Levosulpiride (75mg) + Esomeprazole (40mg)
Cheaper alternative availability
This medicine doesn't have a cheaper alternative with the same composition. Our health advisors can help you find other savings options based on your prescription.
Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Medical applications
Esofine-LS Capsule SR is a combination pharmaceutical formulation containing Levosulpiride 75 mg and Esomeprazole 40 mg, designed for the management of gastrointestinal disorders. Levosulpiride, a selective dopamine D2 receptor antagonist, exhibits prokinetic and antiemetic properties by enhancing gastrointestinal motility and modulating central dopaminergic pathways. Esomeprazole, a proton pump inhibitor, effectively suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme in gastric parietal cells, thereby providing symptomatic relief and promoting mucosal healing in acid-related conditions. The sustained-release formulation ensures prolonged therapeutic plasma concentrations, optimizing efficacy and improving patient compliance. Esofine-LS Capsule SR is indicated for the treatment of gastroesophageal reflux disease (GERD), functional dyspepsia, gastritis, and associated motility disorders. It is particularly beneficial in patients presenting with symptoms such as heartburn, epigastric pain, nausea, and bloating. Administration should be as prescribed by a healthcare professional, with consideration for contraindications including hypersensitivity to either component, and caution in patients with renal or hepatic impairment. Common adverse effects may include headache, dizziness, and mild gastrointestinal disturbances. Regular monitoring and adherence to prescribed dosage are essential to maximize therapeutic outcomes and minimize potential risks.
How to use Esofine-LS Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esofine-LS Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
It is unsafe to consume alcohol with Esofine-LS Capsule SR.
High Risk
Esofine-LS Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Esofine-LS Capsule SR may cause side effects which could affect your ability to drive. Esofine-LS Capsule SR may cause drowsiness, numbness, or dyskinesias, therefore they should be advised to avoid driving and operations requiring supervision.
Exercise Caution
Esofine-LS Capsule SR should be used with caution in patients with severe liver disease. Dose adjustment of Esofine-LS Capsule SR may be needed. Please consult your doctor.
Regular Checkup
Information regarding the use of Esofine-LS Capsule SR during breastfeeding is not available. Please consult your doctor.
Consult Doctor
There is limited information available on the use of Esofine-LS Capsule SR in patients with kidney disease. Please consult your doctor. However, limited data suggest a cautious use of this medicine in these patients.
Regular Checkup
0 reviews for Esofine-LS Capsule SR















