Esofine-DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30mg and Esomeprazole 40mg, designed for the management of gastroesophageal reflux disease (GERD), acid-related dyspepsia, and other upper gastrointestinal disorders. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby reducing symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor (PPI), suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, leading to prolonged reduction of gastric acidity. The synergistic action of these two agents provides effective relief from heartburn, acid regurgitation, and esophageal irritation, while promoting mucosal healing. Esofine-DSR Capsule is indicated for patients requiring both acid suppression and prokinetic therapy, particularly in cases where delayed gastric emptying contributes to symptomatology. It should be administered as prescribed by a healthcare professional, with attention to contraindications such as hypersensitivity to components, and caution in patients with cardiac arrhythmias or hepatic impairment. Common adverse effects may include headache, dry mouth, and gastrointestinal disturbances. Regular monitoring is advised to ensure therapeutic efficacy and safety.

Dosage & How to Use