
Esomeprazole (40mg) + Domperidone (30mg)
Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Esobose Capsule SR contains a combination of Domperidone 30mg and Esomeprazole 40mg, formulated to manage gastrointestinal disorders associated with acid reflux and delayed gastric emptying. Esomeprazole, a proton pump inhibitor, effectively suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, thereby promoting ulcer healing and symptom relief in conditions such as gastroesophageal reflux disease (GERD), erosive esophagitis, and Zollinger-Ellison syndrome. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility and accelerates gastric emptying without affecting gastric acid secretion, providing symptomatic relief from nausea, vomiting, bloating, and discomfort related to delayed gastric emptying or gastroparesis. The sustained-release formulation ensures prolonged therapeutic plasma concentrations, improving patient compliance and efficacy. Esobose Capsule SR is indicated for patients requiring both acid suppression and prokinetic therapy, particularly in cases where monotherapy is insufficient. It should be used under medical supervision, considering contraindications such as hypersensitivity to components, prolactinoma, or cardiac arrhythmias. Caution is advised in patients with hepatic or renal impairment. Common adverse effects may include headache, dry mouth, or gastrointestinal disturbances. Regular monitoring and adherence to prescribed dosage are essential for optimal outcomes.
How to use Esobose Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esobose Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Esobose Capsule SR. Please consult your doctor.
High Risk
Esobose Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Esobose Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Esobose Capsule SR is safe to use in patients with liver disease. No dose adjustment of Esobose Capsule SR is recommended.
Regular Checkup
Esobose Capsule SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Esobose Capsule SR should be used with caution in patients with severe kidney disease. Dose adjustment of Esobose Capsule SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Esobose Capsule SR

Domperidone (30mg) + Esomeprazole (40mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Esobose Capsule SR contains a combination of Domperidone 30mg and Esomeprazole 40mg, formulated to manage gastrointestinal disorders associated with acid reflux and delayed gastric emptying. Esomeprazole, a proton pump inhibitor, effectively suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, thereby promoting ulcer healing and symptom relief in conditions such as gastroesophageal reflux disease (GERD), erosive esophagitis, and Zollinger-Ellison syndrome. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility and accelerates gastric emptying without affecting gastric acid secretion, providing symptomatic relief from nausea, vomiting, bloating, and discomfort related to delayed gastric emptying or gastroparesis. The sustained-release formulation ensures prolonged therapeutic plasma concentrations, improving patient compliance and efficacy. Esobose Capsule SR is indicated for patients requiring both acid suppression and prokinetic therapy, particularly in cases where monotherapy is insufficient. It should be used under medical supervision, considering contraindications such as hypersensitivity to components, prolactinoma, or cardiac arrhythmias. Caution is advised in patients with hepatic or renal impairment. Common adverse effects may include headache, dry mouth, or gastrointestinal disturbances. Regular monitoring and adherence to prescribed dosage are essential for optimal outcomes.
How to use Esobose Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esobose Capsule SR is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Esobose Capsule SR. Please consult your doctor.
High Risk
Esobose Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Esobose Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Esobose Capsule SR is safe to use in patients with liver disease. No dose adjustment of Esobose Capsule SR is recommended.
Regular Checkup
Esobose Capsule SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Esobose Capsule SR should be used with caution in patients with severe kidney disease. Dose adjustment of Esobose Capsule SR may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Esobose Capsule SR















