
Esomeprazole (40mg) + Domperidone (30mg)
Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Esoblok D 30mg/40mg Capsule is a combination medication containing Domperidone 30mg and Esomeprazole 40mg, primarily indicated for the treatment of gastroesophageal reflux disease (GERD), dyspepsia, and related upper gastrointestinal disorders. Esomeprazole, a proton pump inhibitor, acts by selectively inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, thereby suppressing gastric acid secretion and promoting mucosal healing. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility and accelerates gastric emptying, reducing symptoms such as nausea, vomiting, and bloating. The synergistic action of these two agents provides effective relief from acid reflux, heartburn, and associated discomfort by both reducing acid production and improving gastric motility. Esoblok D is generally well tolerated; however, it should be used with caution in patients with known hypersensitivity to either component, significant hepatic impairment, or cardiac arrhythmias. Common adverse effects may include headache, dry mouth, abdominal cramps, and, rarely, extrapyramidal symptoms. It is advisable to administer the capsule before meals for optimal efficacy. Patients should consult healthcare professionals before use, especially if pregnant, breastfeeding, or on concomitant medications that may interact with either Domperidone or Esomeprazole.
How to use Esoblok D Capsule Take this medicine in the dose and duration as advised by your doctor. Esoblok D 30mg/40mg Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Esoblok D 30mg/40mg Capsule. Please consult your doctor.
High Risk
Esoblok D 30mg/40mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Esoblok D 30mg/40mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Esoblok D 30mg/40mg Capsule is safe to use in patients with liver disease. No dose adjustment of Esoblok D 30mg/40mg Capsule is recommended.
Regular Checkup
Esoblok D 30mg/40mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Esoblok D 30mg/40mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Esoblok D 30mg/40mg Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Esoblok D 30mg/40mg Capsule

Domperidone (30mg) + Esomeprazole (40mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Medical applications
Esoblok D 30mg/40mg Capsule is a combination medication containing Domperidone 30mg and Esomeprazole 40mg, primarily indicated for the treatment of gastroesophageal reflux disease (GERD), dyspepsia, and related upper gastrointestinal disorders. Esomeprazole, a proton pump inhibitor, acts by selectively inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, thereby suppressing gastric acid secretion and promoting mucosal healing. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility and accelerates gastric emptying, reducing symptoms such as nausea, vomiting, and bloating. The synergistic action of these two agents provides effective relief from acid reflux, heartburn, and associated discomfort by both reducing acid production and improving gastric motility. Esoblok D is generally well tolerated; however, it should be used with caution in patients with known hypersensitivity to either component, significant hepatic impairment, or cardiac arrhythmias. Common adverse effects may include headache, dry mouth, abdominal cramps, and, rarely, extrapyramidal symptoms. It is advisable to administer the capsule before meals for optimal efficacy. Patients should consult healthcare professionals before use, especially if pregnant, breastfeeding, or on concomitant medications that may interact with either Domperidone or Esomeprazole.
How to use Esoblok D Capsule Take this medicine in the dose and duration as advised by your doctor. Esoblok D 30mg/40mg Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Esoblok D 30mg/40mg Capsule. Please consult your doctor.
High Risk
Esoblok D 30mg/40mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Esoblok D 30mg/40mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Esoblok D 30mg/40mg Capsule is safe to use in patients with liver disease. No dose adjustment of Esoblok D 30mg/40mg Capsule is recommended.
Regular Checkup
Esoblok D 30mg/40mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Esoblok D 30mg/40mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Esoblok D 30mg/40mg Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Esoblok D 30mg/40mg Capsule















