
Domperidone (30mg) + Esomeprazole (40mg)
Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Medical applications
Esmozole DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30 mg and Esomeprazole 40 mg, designed for the effective management of gastroesophageal reflux disease (GERD), acid reflux, and related upper gastrointestinal disorders. Esomeprazole, a proton pump inhibitor (PPI), acts by selectively inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, thereby suppressing gastric acid secretion and promoting mucosal healing. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility and accelerates gastric emptying, providing symptomatic relief from nausea, vomiting, and bloating associated with delayed gastric emptying and reflux. The dual action of Esmozole DSR Capsule addresses both acid suppression and motility enhancement, offering comprehensive symptom control in patients with erosive esophagitis, non-ulcer dyspepsia, and functional dyspepsia. It is generally well-tolerated; however, caution is advised in patients with cardiac arrhythmias or electrolyte imbalances due to Domperidone’s potential to prolong the QT interval. Esmozole DSR should be administered under medical supervision, with dosage adjustments based on clinical response and patient tolerance. This combination therapy improves patient compliance by reducing pill burden while effectively managing complex gastrointestinal symptoms.
How to use Esmozole D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esmozole DSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Esmozole DSR Capsule. Please consult your doctor.
High Risk
Esmozole DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Esmozole DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Esmozole DSR Capsule is safe to use in patients with liver disease. No dose adjustment of Esmozole DSR Capsule is recommended.
Regular Checkup
Esmozole DSR Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Esmozole DSR Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Esmozole DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Esmozole DSR Capsule

Domperidone (30mg) + Esomeprazole (40mg)
Cheaper alternative availability
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Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Medical applications
Esmozole DSR Capsule is a combination pharmaceutical formulation containing Domperidone 30 mg and Esomeprazole 40 mg, designed for the effective management of gastroesophageal reflux disease (GERD), acid reflux, and related upper gastrointestinal disorders. Esomeprazole, a proton pump inhibitor (PPI), acts by selectively inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, thereby suppressing gastric acid secretion and promoting mucosal healing. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility and accelerates gastric emptying, providing symptomatic relief from nausea, vomiting, and bloating associated with delayed gastric emptying and reflux. The dual action of Esmozole DSR Capsule addresses both acid suppression and motility enhancement, offering comprehensive symptom control in patients with erosive esophagitis, non-ulcer dyspepsia, and functional dyspepsia. It is generally well-tolerated; however, caution is advised in patients with cardiac arrhythmias or electrolyte imbalances due to Domperidone’s potential to prolong the QT interval. Esmozole DSR should be administered under medical supervision, with dosage adjustments based on clinical response and patient tolerance. This combination therapy improves patient compliance by reducing pill burden while effectively managing complex gastrointestinal symptoms.
How to use Esmozole D Capsule SR Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esmozole DSR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Esmozole DSR Capsule. Please consult your doctor.
High Risk
Esmozole DSR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Esmozole DSR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Esmozole DSR Capsule is safe to use in patients with liver disease. No dose adjustment of Esmozole DSR Capsule is recommended.
Regular Checkup
Esmozole DSR Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Esmozole DSR Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Esmozole DSR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Esmozole DSR Capsule















