
Domperidone (30mg) + Esomeprazole (40mg)
Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Medical applications
Esmojet-SR Capsule is a combination pharmaceutical formulation containing Domperidone 30 mg and Esomeprazole 40 mg, designed for the management of gastrointestinal disorders associated with acid reflux and delayed gastric emptying. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor (PPI), effectively suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system in gastric parietal cells, providing symptomatic relief from gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcers. The sustained-release formulation ensures prolonged therapeutic plasma concentrations, enhancing efficacy and patient compliance by reducing dosing frequency. Esmojet-SR is indicated for patients requiring combined prokinetic and acid-suppressive therapy, particularly in cases where monotherapy is insufficient. It should be administered under medical supervision, with caution advised in patients with underlying cardiac conditions or those on medications that may interact with Domperidone or Esomeprazole. Common adverse effects may include headache, dry mouth, and gastrointestinal disturbances. Contraindications include hypersensitivity to either component and concurrent use with QT-prolonging agents. Proper diagnosis and adherence to prescribed dosage are essential for optimal therapeutic outcomes.
How to use Esmojet Capsule PR Use it as advised by your doctor or check the label for directions before use. Esmojet-SR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Esmojet-SR Capsule. Please consult your doctor.
High Risk
Esmojet-SR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Esmojet-SR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Esmojet-SR Capsule is safe to use in patients with liver disease. No dose adjustment of Esmojet-SR Capsule is recommended.
Regular Checkup
Esmojet-SR Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Esmojet-SR Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Esmojet-SR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Esmojet-SR Capsule

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Active composition
+1 more active ingredient
Domperidone antagonizes dopamine D2 receptors in the chemoreceptor trigger zone, inhibiting nausea and vomiting.
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Medical applications
Esmojet-SR Capsule is a combination pharmaceutical formulation containing Domperidone 30 mg and Esomeprazole 40 mg, designed for the management of gastrointestinal disorders associated with acid reflux and delayed gastric emptying. Domperidone, a peripheral dopamine D2 receptor antagonist, facilitates gastric motility and accelerates gastric emptying, thereby alleviating symptoms such as nausea, vomiting, and bloating. Esomeprazole, a proton pump inhibitor (PPI), effectively suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system in gastric parietal cells, providing symptomatic relief from gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcers. The sustained-release formulation ensures prolonged therapeutic plasma concentrations, enhancing efficacy and patient compliance by reducing dosing frequency. Esmojet-SR is indicated for patients requiring combined prokinetic and acid-suppressive therapy, particularly in cases where monotherapy is insufficient. It should be administered under medical supervision, with caution advised in patients with underlying cardiac conditions or those on medications that may interact with Domperidone or Esomeprazole. Common adverse effects may include headache, dry mouth, and gastrointestinal disturbances. Contraindications include hypersensitivity to either component and concurrent use with QT-prolonging agents. Proper diagnosis and adherence to prescribed dosage are essential for optimal therapeutic outcomes.
How to use Esmojet Capsule PR Use it as advised by your doctor or check the label for directions before use. Esmojet-SR Capsule is to be taken empty stomach.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Caution is advised when consuming alcohol with Esmojet-SR Capsule. Please consult your doctor.
High Risk
Esmojet-SR Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
Esmojet-SR Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Exercise Caution
Esmojet-SR Capsule is safe to use in patients with liver disease. No dose adjustment of Esmojet-SR Capsule is recommended.
Regular Checkup
Esmojet-SR Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult Doctor
Esmojet-SR Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Esmojet-SR Capsule may be needed. Please consult your doctor.
Regular Checkup
0 reviews for Esmojet-SR Capsule















