Esium IT Capsule
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Esomeprazole (40mg) + Itopride (150mg)
Strip of 10 capsules • Capsule
A valid prescription is required for this medicine.
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Active composition
+1 more active ingredient
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing gastric acid secretion.
Itopride increases acetylcholine levels, enhancing gastrointestinal motility and facilitating food movement through the digestive tract.
Medical applications
Esium IT Capsule is a combination pharmaceutical formulation containing Esomeprazole 40 mg and Itopride 150 mg, designed for the effective management of gastrointestinal disorders characterized by acid-related symptoms and impaired motility. Esomeprazole, a proton pump inhibitor, acts by selectively inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, thereby suppressing gastric acid secretion and providing symptomatic relief in conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and erosive esophagitis.
Itopride, a prokinetic agent, enhances gastrointestinal motility by antagonizing dopamine D2 receptors and inhibiting acetylcholinesterase activity, which facilitates gastric emptying and alleviates symptoms of functional dyspepsia, including bloating, nausea, and early satiety. The synergistic action of Esium IT Capsule addresses both acid suppression and motility enhancement, offering comprehensive therapeutic benefits in patients with overlapping symptoms of acid reflux and delayed gastric emptying.
This combination is generally well tolerated; however, it should be used under medical supervision, particularly in patients with known hypersensitivity to either component, significant hepatic or renal impairment, or underlying cardiac conditions. Esium IT Capsule is intended for oral administration and should be taken as prescribed to optimize clinical outcomes.
How to use Esium IT Capsule Take this medicine in the dose and duration as advised by your doctor. Esium IT Capsule is to be taken empty stomach.
Important precautions
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Caution is advised when consuming alcohol with Esium IT Capsule. Please consult your doctor.
High Risk
Esium IT Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Medical Advice
It is not known whether Esium IT Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Exercise Caution
Esium IT Capsule should be used with caution in patients with severe liver disease. Dose adjustment of Esium IT Capsule may be needed. Please consult your doctor.
Regular Checkup
Information regarding the use of Esium IT Capsule during breastfeeding is not available. Please consult your doctor.
Consult Doctor
There is limited information available on the use of Esium IT Capsule in patients with kidney disease. Please consult your doctor.
Regular Checkup
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