
Sodium Valproate (333mg) + Valproic Acid (145mg)
Active composition
+1 more active ingredient
Sodium Valproate increases GABAergic neurotransmission, stabilizing neuronal excitability and reducing seizure activity.
Valproic Acid increases GABA levels in the brain by inhibiting GABA transaminase, thereby reducing neuronal excitability and stabilizing electrical activity.
Medical applications
Epilex Chrono 500 Eazy Glide Tablet CR is a controlled-release formulation containing Sodium Valproate (333 mg) and Valproic Acid (145 mg), indicated for the management of epilepsy and seizure disorders. This combination acts as an anticonvulsant by increasing gamma-aminobutyric acid (GABA) levels in the brain, thereby stabilizing neuronal activity and preventing seizure propagation. The controlled-release mechanism ensures a steady plasma concentration, enhancing therapeutic efficacy while minimizing peak-related side effects. Epilex Chrono 500 is utilized in the treatment of various seizure types, including generalized tonic-clonic, absence, and complex partial seizures. It may also be prescribed for bipolar disorder and migraine prophylaxis under specialist guidance. Dosage should be individualized based on clinical response and tolerability, with regular monitoring of liver function, blood counts, and plasma drug levels recommended due to potential hepatotoxicity and hematological effects. Common adverse reactions include gastrointestinal disturbances, tremor, weight gain, and sedation. Caution is advised in patients with hepatic impairment, mitochondrial disorders, or pancreatitis history. Epilex Chrono 500 should not be discontinued abruptly to avoid precipitating seizures. This formulation offers improved patient compliance through once or twice-daily dosing, contributing to better seizure control and quality of life in affected individuals.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Epilex Chrono 500 Eazy Glide Tablet CR is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
High Risk
Epilex Chrono 500 Eazy Glide Tablet CR is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Medical Advice
Epilex Chrono 500 Eazy Glide Tablet CR is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Epilex Chrono 500 Eazy Glide Tablet CR may not be needed in these patients. Please consult your doctor. However, talk to your doctor if you have any underlying kidney disease.
Exercise Caution
Epilex Chrono 500 Eazy Glide Tablet CR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
Epilex Chrono 500 Eazy Glide Tablet CR should be used with caution in patients with liver disease. Dose adjustment of Epilex Chrono 500 Eazy Glide Tablet CR may be needed. Please consult your doctor. Use of Epilex Chrono 500 Eazy Glide Tablet CR is not recommended in patients with severe liver disease and active liver disease.
Regular Checkup
0 reviews for Epilex Chrono 500 Eazy Glide Tablet CR

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Active composition
+1 more active ingredient
Sodium Valproate increases GABAergic neurotransmission, stabilizing neuronal excitability and reducing seizure activity.
Valproic Acid increases GABA levels in the brain by inhibiting GABA transaminase, thereby reducing neuronal excitability and stabilizing electrical activity.
Medical applications
Epilex Chrono 500 Eazy Glide Tablet CR is a controlled-release formulation containing Sodium Valproate (333 mg) and Valproic Acid (145 mg), indicated for the management of epilepsy and seizure disorders. This combination acts as an anticonvulsant by increasing gamma-aminobutyric acid (GABA) levels in the brain, thereby stabilizing neuronal activity and preventing seizure propagation. The controlled-release mechanism ensures a steady plasma concentration, enhancing therapeutic efficacy while minimizing peak-related side effects. Epilex Chrono 500 is utilized in the treatment of various seizure types, including generalized tonic-clonic, absence, and complex partial seizures. It may also be prescribed for bipolar disorder and migraine prophylaxis under specialist guidance. Dosage should be individualized based on clinical response and tolerability, with regular monitoring of liver function, blood counts, and plasma drug levels recommended due to potential hepatotoxicity and hematological effects. Common adverse reactions include gastrointestinal disturbances, tremor, weight gain, and sedation. Caution is advised in patients with hepatic impairment, mitochondrial disorders, or pancreatitis history. Epilex Chrono 500 should not be discontinued abruptly to avoid precipitating seizures. This formulation offers improved patient compliance through once or twice-daily dosing, contributing to better seizure control and quality of life in affected individuals.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Epilex Chrono 500 Eazy Glide Tablet CR is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
High Risk
Epilex Chrono 500 Eazy Glide Tablet CR is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Medical Advice
Epilex Chrono 500 Eazy Glide Tablet CR is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Epilex Chrono 500 Eazy Glide Tablet CR may not be needed in these patients. Please consult your doctor. However, talk to your doctor if you have any underlying kidney disease.
Exercise Caution
Epilex Chrono 500 Eazy Glide Tablet CR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
Epilex Chrono 500 Eazy Glide Tablet CR should be used with caution in patients with liver disease. Dose adjustment of Epilex Chrono 500 Eazy Glide Tablet CR may be needed. Please consult your doctor. Use of Epilex Chrono 500 Eazy Glide Tablet CR is not recommended in patients with severe liver disease and active liver disease.
Regular Checkup
0 reviews for Epilex Chrono 500 Eazy Glide Tablet CR















