
Sodium Valproate (135mg) + Valproic Acid (58mg)
Active composition
+1 more active ingredient
Sodium Valproate increases GABAergic neurotransmission, stabilizing neuronal excitability and reducing seizure activity.
Valproic Acid increases GABA levels in the brain by inhibiting GABA transaminase, thereby reducing neuronal excitability and stabilizing electrical activity.
Medical applications
Epilex Chrono 200 Tablet CR Eazy Glide is a controlled-release antiepileptic formulation containing Sodium Valproate (135 mg) and Valproic Acid (58 mg), designed to provide sustained therapeutic plasma concentrations for effective seizure management. This combination is indicated for the treatment of various types of epilepsy, including generalized tonic-clonic seizures, absence seizures, and complex partial seizures. The controlled-release mechanism ensures a gradual release of active ingredients, enhancing patient compliance by reducing dosing frequency and minimizing peak-related side effects. Sodium Valproate and Valproic Acid act primarily by increasing gamma-aminobutyric acid (GABA) levels in the brain, thereby stabilizing neuronal membranes and preventing abnormal electrical discharges. Epilex Chrono 200 is also utilized as a mood stabilizer in bipolar disorder and for prophylaxis of migraine headaches. It should be administered under medical supervision with regular monitoring of liver function, blood counts, and plasma drug levels to avoid potential adverse effects such as hepatotoxicity, thrombocytopenia, and teratogenicity. Dose adjustments may be necessary in patients with hepatic impairment or concomitant use of other antiepileptic drugs. Patients are advised to adhere strictly to prescribed dosages and report any unusual symptoms promptly to their healthcare provider.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Epilex Chrono 200 Tablet CR Eazy Glide is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
High Risk
Epilex Chrono 200 Tablet CR Eazy Glide is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Medical Advice
Epilex Chrono 200 Tablet CR Eazy Glide is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Epilex Chrono 200 Tablet CR Eazy Glide may not be needed in these patients. Please consult your doctor. However, talk to your doctor if you have any underlying kidney disease.
Exercise Caution
Epilex Chrono 200 Tablet CR Eazy Glide may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
Epilex Chrono 200 Tablet CR Eazy Glide should be used with caution in patients with liver disease. Dose adjustment of Epilex Chrono 200 Tablet CR Eazy Glide may be needed. Please consult your doctor. Use of Epilex Chrono 200 Tablet CR Eazy Glide is not recommended in patients with severe liver disease and active liver disease.
Regular Checkup
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Active composition
+1 more active ingredient
Sodium Valproate increases GABAergic neurotransmission, stabilizing neuronal excitability and reducing seizure activity.
Valproic Acid increases GABA levels in the brain by inhibiting GABA transaminase, thereby reducing neuronal excitability and stabilizing electrical activity.
Medical applications
Epilex Chrono 200 Tablet CR Eazy Glide is a controlled-release antiepileptic formulation containing Sodium Valproate (135 mg) and Valproic Acid (58 mg), designed to provide sustained therapeutic plasma concentrations for effective seizure management. This combination is indicated for the treatment of various types of epilepsy, including generalized tonic-clonic seizures, absence seizures, and complex partial seizures. The controlled-release mechanism ensures a gradual release of active ingredients, enhancing patient compliance by reducing dosing frequency and minimizing peak-related side effects. Sodium Valproate and Valproic Acid act primarily by increasing gamma-aminobutyric acid (GABA) levels in the brain, thereby stabilizing neuronal membranes and preventing abnormal electrical discharges. Epilex Chrono 200 is also utilized as a mood stabilizer in bipolar disorder and for prophylaxis of migraine headaches. It should be administered under medical supervision with regular monitoring of liver function, blood counts, and plasma drug levels to avoid potential adverse effects such as hepatotoxicity, thrombocytopenia, and teratogenicity. Dose adjustments may be necessary in patients with hepatic impairment or concomitant use of other antiepileptic drugs. Patients are advised to adhere strictly to prescribed dosages and report any unusual symptoms promptly to their healthcare provider.
Dosage information not available. Please consult your doctor or pharmacist.
Important precautions
Based on clinical trials and patient reports.
Overall Tolerance
Common Side Effects
Epilex Chrono 200 Tablet CR Eazy Glide is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
High Risk
Epilex Chrono 200 Tablet CR Eazy Glide is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Medical Advice
Epilex Chrono 200 Tablet CR Eazy Glide is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Epilex Chrono 200 Tablet CR Eazy Glide may not be needed in these patients. Please consult your doctor. However, talk to your doctor if you have any underlying kidney disease.
Exercise Caution
Epilex Chrono 200 Tablet CR Eazy Glide may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
Epilex Chrono 200 Tablet CR Eazy Glide should be used with caution in patients with liver disease. Dose adjustment of Epilex Chrono 200 Tablet CR Eazy Glide may be needed. Please consult your doctor. Use of Epilex Chrono 200 Tablet CR Eazy Glide is not recommended in patients with severe liver disease and active liver disease.
Regular Checkup
0 reviews for Epilex Chrono 200 Tablet CR Eazy Glide















