Epiford 500 CR Tablet
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1 units • OtherPrescription requiredSchedule H
Epiford 500 CR Tablet
Sodium Valproate (333mg) + Valproic Acid (145mg)
₹97.41
1 units • Other
A valid prescription is required for this medicine.
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Active composition
Valproic Acid 145 mg
+1 more active ingredient
How It Works
Valproic Acid increases GABA levels in the brain by inhibiting GABA transaminase, thereby reducing neuronal excitability and stabilizing electrical activity.
Sodium Valproate increases GABAergic neurotransmission, stabilizing neuronal excitability and reducing seizure activity.
Medicine Strength
145 mg
All Active Ingredients
Valproic Acid145 mg
Sodium Valproate333 mg
Uses & Benefits
Medical applications
Migraine
Epiford 500 CR Tablet contains a combination of Sodium Valproate (333 mg) and Valproic Acid (145 mg), formulated as a controlled-release preparation for the management of epilepsy and related neurological disorders. This medication acts primarily by increasing the availability of gamma-aminobutyric acid (GABA) in the brain, an inhibitory neurotransmitter that helps stabilize neuronal activity and prevent seizure propagation.
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Epiford 500 CR is indicated for the treatment of various seizure types including generalized tonic-clonic seizures, absence seizures, and complex partial seizures. The controlled-release formulation ensures a sustained therapeutic plasma concentration, improving compliance and minimizing peak-related side effects. Additionally, it may be used in the management of bipolar disorder and for migraine prophylaxis under specialist supervision.
Dosage should be individualized based on clinical response and serum drug levels, with careful monitoring for adverse effects such as hepatotoxicity, thrombocytopenia, and gastrointestinal disturbances. Caution is advised in patients with hepatic impairment, mitochondrial disorders, or a history of pancreatitis. Regular liver function tests and blood counts are recommended during therapy.
Epiford 500 CR should be prescribed and monitored by healthcare professionals experienced in epilepsy management to optimize therapeutic outcomes and minimize risks.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side effects
Side-effect information is not available for this medicine. Please consult your doctor or pharmacist.
Safety Advice
Alcohol
Epiford 500 CR Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
High Risk
Pregnancy
Epiford 500 CR Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Medical Advice
Driving
Epiford 500 CR Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Epiford 500 CR Tablet may not be needed in these patients. Please consult your doctor. However, talk to your doctor if you have any underlying kidney disease.
Exercise Caution
Breastfeeding
Epiford 500 CR Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Consult Doctor
Kidney
Epiford 500 CR Tablet should be used with caution in patients with liver disease. Dose adjustment of Epiford 500 CR Tablet may be needed. Please consult your doctor. Use of Epiford 500 CR Tablet is not recommended in patients with severe liver disease and active liver disease.
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