Zefrox LB 200mg Tablet is a combination antibiotic formulation containing Cefixime 200mg and Lactobacillus 2.5 Billion Spores, designed for the effective treatment of bacterial infections while maintaining gastrointestinal flora balance. Cefixime, a third-generation cephalosporin antibiotic, exhibits broad-spectrum activity against various gram-positive and gram-negative bacteria by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. It is commonly prescribed for respiratory tract infections, urinary tract infections, otitis media, and uncomplicated gonorrhea. The inclusion of Lactobacillus, a probiotic, helps restore and maintain the natural intestinal microflora, reducing the risk of antibiotic-associated diarrhea and other gastrointestinal disturbances often caused by antibiotic therapy. Zefrox LB is indicated in patients requiring antibiotic treatment who are at risk of dysbiosis or those with a history of antibiotic-induced gastrointestinal side effects. The combination ensures effective eradication of pathogenic bacteria while supporting gut health. It is important to use this medication under medical supervision, adhering to prescribed dosages and duration to prevent resistance development. Caution is advised in patients with known hypersensitivity to cephalosporins or probiotics. This formulation offers a balanced approach to infection management by combining antimicrobial efficacy with probiotic support.