Xgaba NT 100mg/10mg Tablet is a combination medication containing Gabapentin 100mg and Nortriptyline 10mg, indicated for the management of neuropathic pain and certain types of chronic pain conditions. Gabapentin, an anticonvulsant, modulates calcium channels to reduce neuronal excitability, thereby alleviating neuropathic pain symptoms. Nortriptyline, a tricyclic antidepressant, enhances noradrenergic and serotonergic neurotransmission by inhibiting the reuptake of norepinephrine and serotonin, contributing to analgesic effects and mood stabilization. This dual-action formulation is particularly beneficial in patients who require both neuropathic pain relief and improvement in associated depressive symptoms. Xgaba NT is typically prescribed when monotherapy is insufficient or when synergistic effects are desired. The dosage should be individualized based on clinical response and tolerability, with careful monitoring for adverse effects such as dizziness, sedation, dry mouth, and potential cardiac arrhythmias associated with tricyclic antidepressants. Caution is advised in patients with a history of cardiovascular disease, glaucoma, or renal impairment. Xgaba NT should be used under strict medical supervision, with gradual dose adjustments to minimize withdrawal symptoms and optimize therapeutic outcomes. It is contraindicated in patients with hypersensitivity to either component and during the acute recovery phase following myocardial infarction.