NT Peg LS Tablet
NT Peg LS Tablet
Pregabalin (50mg) + Nortriptyline (10mg)
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About This Medicine
Product description & overview
NT Peg LS Tablet contains a combination of Pregabalin 50mg and Nortriptyline 10mg, formulated for the management of neuropathic pain and certain types of chronic pain disorders. Pregabalin is an anticonvulsant and neuropathic pain agent that modulates calcium channels to reduce neurotransmitter release, thereby diminishing nerve pain and seizure activity. Nortriptyline, a tricyclic antidepressant, exerts analgesic effects by inhibiting the reuptake of norepinephrine and serotonin, enhancing descending inhibitory pain pathways. This combination provides a synergistic effect, improving pain control in conditions such as diabetic neuropathy, postherpetic neuralgia, and fibromyalgia. NT Peg LS Tablet is indicated for patients who require both neuropathic pain relief and mood stabilization, particularly when monotherapy is insufficient. The medication should be used under medical supervision, with careful dose titration to minimize adverse effects such as dizziness, sedation, dry mouth, and potential cardiovascular effects associated with nortriptyline. Caution is advised in patients with a history of cardiac disease, glaucoma, or renal impairment. NT Peg LS Tablet is contraindicated in individuals with hypersensitivity to either component. Regular monitoring and adherence to prescribed dosing are essential to optimize therapeutic outcomes and ensure patient safety.
Active composition
Pregabalin 50 mg
+1 more active ingredient
About Pregabalin
Pregabalin is an anticonvulsant used to treat neuropathic pain and epilepsy. It works by calming overactive nerves, reducing pain and seizure frequency. Pregabalin is effective in managing chronic pain and seizure disorders. Common side effects may include dizziness and weight gain, but these usually resolve over time. In summary, Pregabalin is important for managing nerve pain and seizures.
How It Works
Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels, inhibiting excitatory neurotransmitter release and reducing neuronal excitability.
All Active Ingredients
Nortriptyline
Nortriptyline inhibits the reuptake of norepinephrine and serotonin, increasing their levels in the synaptic cleft and enhancing mood.
Dosage & How to Use
Dosage information not available. Please consult your doctor or pharmacist.
Safety Advice
Important precautions
Side Effect Occurrence
Based on clinical trials and patient reports.
Overall Tolerance
Most patients tolerate well
Common Side Effects
Safety Advice
Alcohol
NT Peg LS Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
High Risk
Pregnancy
NT Peg LS Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Medical Advice
Driving
NT Peg LS Tablet should be used with caution in patients with kidney disease. Dose adjustment of NT Peg LS Tablet may be needed. Please consult your doctor.
Exercise Caution
Breastfeeding
NT Peg LS Tablet may cause side effects which could affect your ability to drive. As NT Peg LS Tablet may affect your alertness which may affect your ability to drive.
Consult Doctor
Kidney
NT Peg LS Tablet should be used with caution in patients with liver disease. Dose adjustment of NT Peg LS Tablet may be needed. Please consult your doctor.
Regular Checkup
Customer Reviews
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