Mecorn-NP Tablet is a combination pharmaceutical formulation containing Pregabalin 75mg, Nortriptyline 10mg, and Methylcobalamin 1500mcg, designed for the management of neuropathic pain and associated neurological conditions. Pregabalin, an anticonvulsant and analgesic agent, modulates calcium channels to reduce neurotransmitter release, thereby alleviating neuropathic pain and improving nerve function. Nortriptyline, a tricyclic antidepressant, contributes to pain relief by inhibiting the reuptake of norepinephrine and serotonin, enhancing descending inhibitory pain pathways. Methylcobalamin, an active form of vitamin B12, supports nerve regeneration and repair through its role in myelin sheath synthesis and neuronal metabolism. The synergistic action of these components makes Mecorn-NP effective in treating peripheral neuropathies, diabetic neuropathy, post-herpetic neuralgia, and other chronic neuropathic pain syndromes. This combination also helps improve nerve conduction velocity and reduces symptoms such as burning, tingling, and numbness. Mecorn-NP should be administered under medical supervision, with dosage tailored to individual patient needs. Caution is advised in patients with renal impairment, cardiac conditions, or those on concomitant CNS depressants. Common side effects may include dizziness, drowsiness, dry mouth, and gastrointestinal disturbances. Regular monitoring is recommended to optimize therapeutic outcomes and minimize adverse effects.