Looz Enema Mini contains Lactulose 20% w/v, a synthetic disaccharide used primarily as a laxative for the treatment of constipation. Lactulose is not absorbed in the upper gastrointestinal tract; instead, it reaches the colon where it is metabolized by colonic bacteria into low molecular weight organic acids, resulting in an osmotic effect that increases fecal water content, softening stools and promoting bowel movements. This enema formulation provides a rapid onset of action, typically producing results within 15 to 30 minutes, making it suitable for patients requiring prompt relief from acute constipation or for bowel cleansing prior to diagnostic procedures. Looz Enema Mini is administered rectally, allowing direct delivery to the distal colon and minimizing systemic absorption, thereby reducing the risk of systemic side effects. It is indicated in adults and pediatric patients for short-term management of constipation and fecal impaction. Caution is advised in patients with abdominal pain of unknown origin, intestinal obstruction, or hypersensitivity to lactulose. Adverse effects may include abdominal discomfort, cramping, flatulence, and diarrhea if used excessively. Looz Enema Mini should be used under medical supervision, with attention to hydration status and electrolyte balance during prolonged use.