Looz Oral Solution contains Lactulose 10gm per 15ml, a synthetic disaccharide used primarily as a laxative for the treatment of constipation. Lactulose is not absorbed in the small intestine but undergoes fermentation by colonic bacteria, producing organic acids that increase osmotic pressure and promote water retention in the colon. This results in softened stools and enhanced bowel motility, facilitating easier defecation. Additionally, Looz Oral Solution is indicated in the management of hepatic encephalopathy by reducing blood ammonia levels through acidification of the colonic contents, which converts ammonia to ammonium ions that are less readily absorbed. The solution is administered orally, with dosage individualized based on the severity of constipation or hepatic encephalopathy. Common side effects may include flatulence, abdominal discomfort, and diarrhea if overdosed. Caution is advised in patients with galactosemia or those requiring electrolyte monitoring due to potential disturbances. Looz Oral Solution is contraindicated in cases of intestinal obstruction or acute surgical abdomen. It is essential to maintain adequate hydration during therapy. Overall, Looz Oral Solution offers an effective and well-tolerated option for managing chronic constipation and hepatic encephalopathy under medical supervision.