Lactosan Oral Solution Sugar Free contains lactulose 10gm per 15ml and is indicated primarily for the treatment of chronic constipation and hepatic encephalopathy. Lactulose is a synthetic disaccharide that is not absorbed in the small intestine but undergoes fermentation by colonic bacteria, resulting in the production of organic acids that lower colonic pH. This acidification promotes osmotic retention of water in the bowel, thereby softening stools and facilitating bowel movements. Additionally, in hepatic encephalopathy, lactulose reduces blood ammonia levels by converting ammonia to non-absorbable ammonium ions in the colon, thus decreasing systemic absorption and neurotoxic effects. The sugar-free formulation is suitable for patients requiring dietary sugar restrictions, including diabetics. Lactosan Oral Solution is administered orally, with dosage individualized based on patient response and clinical condition; typical doses range from 15 to 30 ml daily for constipation, divided into one or two doses. Common adverse effects may include flatulence, abdominal discomfort, and diarrhea, which are generally transient and dose-dependent. Lactosan should be used cautiously in patients with galactose intolerance or fructose malabsorption. It is contraindicated in cases of galactosemia and intestinal obstruction. Regular monitoring and adherence to prescribed dosing ensure optimal therapeutic outcomes.