Lefomycs 10 Tablet contains Leflunomide 10 mg, a disease-modifying antirheumatic drug (DMARD) primarily indicated for the treatment of rheumatoid arthritis and psoriatic arthritis. Leflunomide exerts its therapeutic effect by inhibiting dihydroorotate dehydrogenase, a key enzyme involved in pyrimidine synthesis, thereby reducing the proliferation of activated lymphocytes responsible for inflammation and joint damage. This immunomodulatory action helps to alleviate symptoms such as joint pain, swelling, and stiffness, and may slow the progression of structural joint damage. Lefomycs 10 Tablet is typically prescribed as part of a comprehensive treatment regimen and may be used alone or in combination with other agents. It is important to monitor liver function tests, complete blood counts, and blood pressure regularly during therapy due to potential adverse effects including hepatotoxicity, hematologic abnormalities, and hypertension. Leflunomide is contraindicated in pregnancy due to teratogenicity; effective contraception is advised for both male and female patients during and after treatment. Patients should be counseled on the importance of adherence to prescribed dosing and regular follow-up to optimize therapeutic outcomes and minimize risks. Lefomycs 10 Tablet provides an effective option for managing autoimmune inflammatory conditions with a well-established safety and efficacy profile.