Methora 20 Tablet contains Methotrexate 20 mg, a folate antagonist widely used in the treatment of various medical conditions including certain types of cancer, autoimmune diseases, and ectopic pregnancies. Methotrexate acts by inhibiting dihydrofolate reductase, an enzyme involved in the synthesis of tetrahydrofolate, thereby interfering with DNA synthesis, repair, and cellular replication. This mechanism makes it effective in rapidly dividing cells such as malignant cells and immune system components. Methora 20 is commonly prescribed for conditions such as rheumatoid arthritis, psoriasis, juvenile idiopathic arthritis, and certain leukemias and lymphomas. It is also employed as a chemotherapeutic agent in combination regimens for various malignancies. Due to its potent effects, Methora 20 should be administered under strict medical supervision with regular monitoring of blood counts, liver and kidney function tests to detect potential toxicities early. Common adverse effects include gastrointestinal disturbances, hepatotoxicity, myelosuppression, and mucositis. Patients are advised to avoid alcohol and maintain adequate hydration during therapy. Methora 20 Tablet is contraindicated in pregnancy and breastfeeding due to its teratogenic potential. Dose adjustments may be necessary in patients with renal or hepatic impairment. Proper adherence to prescribed dosing schedules is essential to maximize therapeutic benefits while minimizing risks.