Lactofast Oral Solution Sugar Free contains Lactulose 10gm per 15ml and is a synthetic disaccharide used primarily as a laxative for the treatment of chronic constipation and hepatic encephalopathy. Lactulose works by metabolizing in the colon into low molecular weight organic acids, which acidify the colonic contents, leading to an osmotic effect that increases stool water content, softens stools, and promotes bowel movements. Its sugar-free formulation makes it suitable for patients with diabetes or those requiring dietary sugar restrictions. Lactofast is indicated for patients experiencing constipation due to various causes, including opioid-induced constipation and slow-transit constipation. Additionally, it is employed in managing hepatic encephalopathy by reducing blood ammonia levels through the conversion of ammonia to ammonium ions in the colon, thereby decreasing systemic absorption. The oral solution is administered according to the severity of the condition, with dosage adjustments based on clinical response. Common side effects may include flatulence, abdominal discomfort, and diarrhea, which are generally mild and transient. Lactofast Oral Solution Sugar Free should be used with caution in patients with galactosemia and those with intestinal obstruction. It is contraindicated in cases of hypersensitivity to lactulose or any excipients. Regular monitoring and adherence to prescribed dosage are essential to ensure therapeutic efficacy and minimize adverse effects.