Lacne 10 Capsule contains isotretinoin 10 mg, a retinoid derivative primarily indicated for the treatment of severe recalcitrant nodular acne that is unresponsive to conventional therapies such as antibiotics and topical agents. Isotretinoin exerts its therapeutic effects by reducing sebaceous gland size and sebum production, normalizing follicular keratinization, and exhibiting anti-inflammatory properties, thereby addressing multiple pathogenic factors of acne. Lacne 10 Capsule is prescribed under strict medical supervision due to its potent efficacy and potential for serious adverse effects, including teratogenicity, hepatotoxicity, and lipid abnormalities. Prior to initiation, baseline liver function tests, lipid profile, and pregnancy testing in women of childbearing potential are mandatory. Patients must adhere to recommended dosage and monitoring schedules to minimize risks. Common side effects include dry skin, cheilitis, and photosensitivity, while rare but severe effects may involve mood changes and musculoskeletal symptoms. Lacne 10 Capsule is contraindicated in pregnancy and in patients with hypersensitivity to isotretinoin or vitamin A derivatives. It is essential to counsel patients regarding contraception and avoidance of vitamin A supplements during therapy. This medication should be used only when the benefits outweigh the risks and under close clinical follow-up to ensure safe and effective treatment outcomes.