Isotane 10 Capsule contains isotretinoin 10mg, a retinoid derivative primarily indicated for the treatment of severe recalcitrant nodular acne that is unresponsive to conventional therapies such as antibiotics and topical agents. Isotretinoin exerts its therapeutic effects by reducing sebaceous gland size and sebum production, inhibiting comedogenesis, and exhibiting anti-inflammatory properties. The capsule formulation ensures precise dosing and optimal bioavailability. Isotretinoin is contraindicated in pregnancy due to its high teratogenic potential and requires strict adherence to pregnancy prevention programs during treatment. Common adverse effects include dry skin, cheilitis, conjunctivitis, and transient elevations in liver enzymes and lipid profiles; therefore, regular monitoring of liver function tests and lipid levels is recommended throughout therapy. Patients should be advised to avoid excessive sun exposure and use appropriate skin moisturizers. Dosage is individualized based on patient weight, severity of acne, and response to treatment, typically administered once or twice daily with food to enhance absorption. Isotane 10 Capsule should be prescribed and monitored by healthcare professionals experienced in isotretinoin therapy to ensure safe and effective use. Patient education on potential side effects and adherence to monitoring protocols is essential for optimal outcomes.