IT 10 Tablet contains Isotretinoin 10mg, a systemic retinoid primarily indicated for the treatment of severe recalcitrant nodular acne that is unresponsive to conventional therapies such as antibiotics and topical agents. Isotretinoin, a vitamin A derivative, exerts its therapeutic effects by reducing sebaceous gland size and sebum production, normalizing follicular keratinization, and exhibiting anti-inflammatory properties. This leads to a significant decrease in acne lesion formation and promotes long-term remission. IT 10 Tablet should be administered under strict medical supervision due to its potential for serious adverse effects, including teratogenicity, hepatotoxicity, and lipid abnormalities. Baseline and periodic monitoring of liver function tests, lipid profile, and complete blood counts are recommended during therapy. Female patients of childbearing potential must adhere to rigorous pregnancy prevention measures before, during, and after treatment due to the high risk of fetal malformations. Common side effects may include dry skin, cheilitis, photosensitivity, and mucosal dryness. Dose adjustments or discontinuation may be necessary in the event of severe adverse reactions. IT 10 Tablet is contraindicated in pregnancy, breastfeeding, and patients with hypersensitivity to isotretinoin or vitamin A derivatives. It is essential to counsel patients thoroughly regarding the benefits, risks, and necessary precautions associated with isotretinoin therapy.